Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | AQP1 | P29972 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3716917 | 0.80 | PIK3CA (0.52) | LMNAKDM4EALDH1A1GAAHPGD | |
| SCHEMBL7256671 | 0.78 | KMT2A (0.52) | KMT2AEGFRLMNAKDM4EALDH1A1 | |
| SCHEMBL118131 | 0.76 | SMN1; SMN2 (0.49) | KMT2AAPPEGFRLMNAKDM4E | |
| SCHEMBL3662262 | 0.75 | KDM4E (0.46) | KMT2AAPPEGFRKDM4EALDH1A1 | |
| SCHEMBL1653865 | 0.74 | SMN1; SMN2 (0.47) | KMT2AAPPEGFRLMNAKDM4E | |
| SCHEMBL13087302 | 0.74 | EGFR (0.72) | KMT2AEGFRLMNAKDM4EALDH1A1 | |
| SCHEMBL22119481 | 0.74 | HIF1A (0.41) | KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL19072400 | 0.74 | KMT2A (0.45) | KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL16505504 | 0.73 | NQO2 (0.47) | LMNAKDM4EALDH1A1GAAMAPT | |
| SCHEMBL9316001 | 0.73 | LMNA (0.47) | KMT2AEGFRLMNAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101938905-A | Chemical compounds | SYNGENTA LTD | 2011-01-05 | — | — | CN | disclosed |