Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | KHK | P50053 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | BCDIN3D | Q7Z5W3 | 8/20 | 0.38 |
| ▸ | AXL | P30530 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.38 |
| ▸ | MERTK | Q12866 | 1/20 | 0.38 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.38 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.38 |
| ▸ | PLK4 | O00444 | 1/20 | 0.38 |
| ▸ | PAK4 | O96013 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13943748 | 0.80 | TP53 (0.61) | TP53BCDIN3DPDE2AHTR2C | |
| SCHEMBL13943301 | 0.72 | TP53 (0.66) | TP53BCDIN3DPDE2AHTR2C | |
| SCHEMBL13947367 | 0.67 | TP53 (0.65) | TP53BCDIN3DPDE2AHTR2C | |
| SCHEMBL13944193 | 0.67 | TP53 (0.65) | TP53BCDIN3DPDE2AHTR2C | |
| SCHEMBL2875493 | 0.66 | KDR (0.46) | TP53ALDH1A1CYP1A2HSD17B10 | |
| SCHEMBL13947360 | 0.65 | TP53 (0.62) | TP53ALDH1A1BCDIN3DPLK4PDE2A | |
| SCHEMBL13943257 | 0.65 | TP53 (0.66) | TP53ALDH1A1BCDIN3DHTR2C | |
| SCHEMBL13943258 | 0.64 | BCDIN3D (0.59) | BCDIN3DPLK4PDE2AHTR2C | |
| SCHEMBL2871542 | 0.64 | PDE5A (0.51) | TP53ALDH1A1CYP1A2HSD17B10HTR2C | |
| SCHEMBL13942964 | 0.64 | HTR2C (0.67) | TP53ALDH1A1BCDIN3DAXLMERTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010118367-A2 | ANTIVIRAL PYRIMIDINES | PROGENICS PHARMACEUTICALS, INC. (US) | 2010-10-14 | — | — | WO | disclosed |