Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 7/20 | 0.46 |
| ▸ | RET | P07949 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | TSHR | P16473 | 6/20 | 0.41 |
| ▸ | USP2 | O75604 | 6/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.41 |
| ▸ | TP53 | P04637 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2832269 | 0.69 | PIK3CA (0.46) | ALDH1A1MEN1KMT2ATSHRTP53 | |
| SCHEMBL2879632 | 0.69 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2ATSHRUSP2 | |
| SCHEMBL2856614 | 0.69 | PDE5A (0.55) | ALDH1A1MEN1KMT2ATSHRTP53 | |
| SCHEMBL3185882 | 0.64 | KDM4C (0.47) | ALDH1A1KDM4E | |
| SCHEMBL13943301 | 0.62 | TP53 (0.66) | MEN1KMT2ATP53MAPT | |
| SCHEMBL23579582 | 0.61 | BCDIN3D (0.57) | MEN1KMT2ATP53LMNAMAPT | |
| SCHEMBL30034104 | 0.61 | BCDIN3D (0.57) | MEN1KMT2ATP53LMNAMAPT | |
| SCHEMBL13943257 | 0.61 | TP53 (0.66) | ALDH1A1MEN1KMT2ATP53MAPT | |
| SCHEMBL8762131 | 0.61 | PFKFB3 (0.72) | ALDH1A1MEN1KMT2AMAPTMAPK1 | |
| SCHEMBL2871542 | 0.61 | PDE5A (0.51) | ALDH1A1TSHRUSP2CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010118367-A2 | ANTIVIRAL PYRIMIDINES | PROGENICS PHARMACEUTICALS, INC. (US) | 2010-10-14 | — | — | WO | disclosed |