Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | CFTR | P13569 | 1/20 | 0.44 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13089094 | 0.90 | GAA (0.44) | GAASLC6A2SLC6A4SLC6A3CFTR | |
| SCHEMBL8027681 | 0.86 | CYP19A1 (0.37) | GAASLC6A2SLC6A4SLC6A3CYP19A1 | |
| SCHEMBL13089149 | 0.85 | SLC6A2 (0.40) | GAASLC6A2SLC6A4SLC6A3CYP19A1 | |
| SCHEMBL13089152 | 0.84 | SLC6A2 (0.44) | GAASLC6A2SLC6A4SLC6A3CFTR | |
| SCHEMBL13089180 | 0.83 | SLC6A2 (0.61) | GAASLC6A2SLC6A4SLC6A3CFTR | |
| SCHEMBL10552827 | 0.83 | ESR1 (0.38) | GAASLC6A2SLC6A4SLC6A3CYP19A1 | |
| SCHEMBL13089064 | 0.81 | SLC6A2 (0.41) | GAASLC6A2SLC6A4SLC6A3CFTR | |
| SCHEMBL13089104 | 0.80 | KCNA5 (0.45) | GAASLC6A2SLC6A4SLC6A3CFTR | |
| SCHEMBL13089119 | 0.80 | SLC6A2 (0.39) | GAASLC6A2SLC6A4SLC6A3CFTR | |
| SCHEMBL3028121 | 0.79 | CFTR (0.38) | GAASLC6A2SLC6A4SLC6A3CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100273814-A1 | ((PHENYL)IMIDAZOLYL)METHYLHETEROARYL COMPOUNDS | SINHA SANTOSH C | 2010-10-28 | — | — | US | disclosed |
| US-20100273814-A1 | ((PHENYL)IMIDAZOLYL)METHYLHETEROARYL COMPOUNDS | SINHA SANTOSH C | 2010-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100273814-A1 | ((PHENYL)IMIDAZOLYL)METHYLHETEROARYL COMPOUNDS | CYP11B2, TPMT, COXFA4L2 | GAA 362/4885SLC6A2 2046/4885SLC6A4 1930/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.