Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.30 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8027681 | 0.90 | CYP19A1 (0.37) | SLC6A2SLC6A4SLC6A3GAACYP19A1 | |
| SCHEMBL13089096 | 0.89 | ADRA2A (0.40) | SLC6A2SLC6A4SLC6A3KDM4EMAPT | |
| SCHEMBL13099341 | 0.87 | SLC6A2 (0.33) | SLC6A2SLC6A4SLC6A3KDM4EMAPT | |
| SCHEMBL10552827 | 0.86 | ESR1 (0.38) | SLC6A2SLC6A4SLC6A3GAAMAPT | |
| SCHEMBL13089142 | 0.85 | GAA (0.52) | SLC6A2SLC6A4SLC6A3GAAKDM4E | |
| SCHEMBL13089174 | 0.83 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3CYP19A1 | |
| SCHEMBL13089039 | 0.82 | SLC6A3 (0.57) | SLC6A2SLC6A4SLC6A3GAAKDM4E | |
| SCHEMBL13089106 | 0.81 | CYP19A1 (0.34) | SLC6A2SLC6A4SLC6A3CYP19A1 | |
| SCHEMBL13089114 | 0.81 | SLC6A2 (0.33) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL13089136 | 0.81 | MAPT (0.42) | SLC6A2SLC6A4SLC6A3GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100273814-A1 | ((PHENYL)IMIDAZOLYL)METHYLHETEROARYL COMPOUNDS | SINHA SANTOSH C | 2010-10-28 | — | — | US | disclosed |
| US-20100273814-A1 | ((PHENYL)IMIDAZOLYL)METHYLHETEROARYL COMPOUNDS | SINHA SANTOSH C | 2010-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100273814-A1 | ((PHENYL)IMIDAZOLYL)METHYLHETEROARYL COMPOUNDS | CYP11B2, TPMT, COXFA4L2 | SLC6A2 2046/4885SLC6A4 1930/4885SLC6A3 2604/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.