SCHEMBL13089503

SCHEMBL13089503

CC(=O)O[Si](C)(C)CC[Si](C)(C)C

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.31
LMNA P02545 1/20 0.31
HSD17B10 Q99714 1/20 0.31
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL704202 0.92 ALDH1A1 (0.35) ALDH1A1LMNAHSD17B10TSHR
SCHEMBL12898581 0.83
SCHEMBL12898569 0.83
SCHEMBL705061 0.82 KDM4E (0.35) ALDH1A1LMNAHSD17B10TSHR
SCHEMBL712067 0.82 KDM4E (0.35) ALDH1A1LMNAHSD17B10TSHR
SCHEMBL435046 0.80 ALDH1A1 (0.36) ALDH1A1LMNAHSD17B10TSHR
SCHEMBL13089420 0.80 ALDH1A1 (0.31) ALDH1A1LMNAHSD17B10TSHR
SCHEMBL11671028 0.78
SCHEMBL13089113 0.77 ALDH1A1 (0.32) ALDH1A1LMNAHSD17B10TSHR
SCHEMBL476046 0.76 ALDH1A1 (0.43) ALDH1A1LMNAHSD17B10TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100261925-A1 METHOD FOR PRODUCING SILICON COMPOUND JSR CORPORATION (JP) 2010-10-14 US disclosed
US-20100174103-A1 MATERIAL FOR FORMING SILICON-CONTAINING FILM, AND SILICON-CONTAINING INSULATING FILM AND METHOD FOR FORMING THE SAME JSR CORPORATION (JP) 2010-07-08 US disclosed
US-20100140754-A1 FILM-FORMING MATERIAL, SILICON-CONTAINING INSULATING FILM AND METHOD FOR FORMING THE SAME JSR CORPORATION (JP) 2010-06-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100140754-A1 FILM-FORMING MATERIAL, SILICON-CONTAINING INSULATING FILM AND METHOD FOR FORMING THE SAME RIF1, SAT1, SUV39H2 ALDH1A1 1798/4885LMNA 3661/4885HSD17B10 2541/4885
US-20100261925-A1 METHOD FOR PRODUCING SILICON COMPOUND GMNN, GEMIN5, SEPTIN7 ALDH1A1 3835/4885LMNA 4134/4885HSD17B10 2907/4885
US-20100174103-A1 MATERIAL FOR FORMING SILICON-CONTAINING FILM, AND SILICON-CONTAINING INSULATING FILM AND METHOD FOR FORMING THE SAME PROX1, PYM1, SHROOM3 ALDH1A1 1928/4885LMNA 3565/4885HSD17B10 1839/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.