SCHEMBL13089940

SCHEMBL13089940

Cc1ccccc1N(c1ccccc1)c1ccc(-c2cc3c4cccc(-c5ccc(N(c6ccccc6)c6ccccc6C)cc5)c4ccc3c3ccccc23)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.38
CRHR1 P34998 4/20 0.35
RXRA P19793 1/20 0.32
RXRB P28702 1/20 0.32
MEN1 O00255 1/20 0.31
USP2 O75604 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
MAPK1 P28482 1/20 0.31
CTNNB1 P35222 1/20 0.31
KMT2A Q03164 1/20 0.31
ATM Q13315 1/20 0.31
RXFP1 Q9HBX9 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
ENPP3 O14638 1/20 0.31
ENPP1 P22413 1/20 0.31
TLR8 Q9NR97 1/20 0.31
PDCD1 Q15116 1/20 0.30
CD274 Q9NZQ7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10128664 0.94 KDM4E (0.38) KDM4ECRHR1RXRARXRBMEN1
SCHEMBL22930170 0.86 KDM4E (0.33) KDM4E
SCHEMBL13089942 0.84 CRHR1 (0.39) KDM4ECRHR1MEN1USP2ALDH1A1
SCHEMBL16428804 0.82 TNKS2 (0.39) KDM4ERXRARXRBMEN1MAPT
SCHEMBL7596522 0.82 ENPP3 (0.43) CRHR1ALDH1A1ENPP3ENPP1
SCHEMBL13089941 0.82 ALDH1A1 (0.33) KDM4ECRHR1MEN1USP2ALDH1A1
SCHEMBL7591995 0.82 ENPP3 (0.43) CRHR1ALDH1A1ENPP3ENPP1
SCHEMBL2604757 0.79 CA12 (0.40) CRHR1ALDH1A1ENPP3ENPP1TLR8
SCHEMBL17734776 0.78 ENPP3 (0.40) ALDH1A1ENPP3ENPP1TLR8
SCHEMBL26053539 0.78 HPRT1 (0.40) KDM4EMEN1ALDH1A1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100259163-A1 POLYMER COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2010-10-14 US disclosed
US-20100259163-A1 POLYMER COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2010-10-14 US disclosed