Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 3/20 | 0.45 |
| ▸ | NOS2 | P35228 | 2/20 | 0.45 |
| ▸ | NOS3 | P29474 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 4/20 | 0.38 |
| ▸ | AR | P10275 | 2/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | JAK1 | P23458 | 2/20 | 0.35 |
| ▸ | JAK3 | P52333 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29316983 | 0.81 | CACNA1H (0.39) | NOTUM | |
| SCHEMBL2149212 | 0.78 | NOS1 (0.53) | NOS1NOS2NOS3GRIN2DGRIN3B | |
| SCHEMBL5543671 | 0.77 | NOS1 (0.49) | NOS1NOS2NOS3NOTUMGRIN2D | |
| SCHEMBL5540014 | 0.74 | NOS1 (0.49) | NOS1NOS2NOS3GRIN2DGRIN3B | |
| SCHEMBL5536403 | 0.74 | NOS1 (0.49) | NOS1NOS2NOS3GRIN2DGRIN3B | |
| SCHEMBL13688720 | 0.72 | NOS1 (0.47) | NOS1NOS2NOS3GRIN2DGRIN3B | |
| SCHEMBL13843816 | 0.71 | NOS1 (0.46) | NOS1NOS2NOS3GRIN2DGRIN3B | |
| SCHEMBL12884766 | 0.70 | NOS1 (0.45) | NOS1NOS2NOS3NOTUMGRIN2D | |
| SCHEMBL7788001 | 0.69 | GRIN1 (0.61) | ARGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL9380892 | 0.68 | NOS1 (0.42) | NOS1NOS2NOS3ARGRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010123139-A1 | ARYLCARBOXAMIDE DERIVATIVE HAVING SULFAMOYL GROUP | 持田製薬株式会社 (JP) | 2010-10-28 | — | — | WO | disclosed |