Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15786402 | 0.88 | SLC9A1 (0.58) | SLC9A1KMT2APOLBMEN1MAPT | |
| SCHEMBL20752138 | 0.80 | SLC9A1 (0.52) | SLC9A1ELANEPRTN3ALDH1A1PGR | |
| SCHEMBL89095 | 0.80 | PDE3B (0.52) | SLC9A1KMT2APOLBMEN1MAPT | |
| SCHEMBL8039159 | 0.77 | SLC9A1 (0.66) | SLC9A1KMT2APOLBMEN1MAPT | |
| SCHEMBL3288905 | 0.77 | SLC9A1 (0.47) | SLC9A1PDE3BPDE3APGR | |
| SCHEMBL13091244 | 0.75 | TSHR (0.42) | SLC9A1KMT2APOLBMEN1MAPT | |
| SCHEMBL13340980 | 0.75 | SLC9A1 (0.57) | SLC9A1KMT2APOLBHPGDALDH1A1 | |
| SCHEMBL8365602 | 0.74 | SLC9A1 (1.00) | SLC9A1KMT2APOLBMEN1MAPT | |
| SCHEMBL13091047 | 0.74 | ALDH1A1 (0.47) | KMT2APOLBMEN1MAPTHPGD | |
| SCHEMBL89093 | 0.73 | POLB (0.47) | KMT2APOLBMEN1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010123139-A1 | ARYLCARBOXAMIDE DERIVATIVE HAVING SULFAMOYL GROUP | 持田製薬株式会社 (JP) | 2010-10-28 | — | — | WO | disclosed |