Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 2/20 | 0.52 |
| ▸ | XIAP | P98170 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CDYL | Q9Y232 | 2/20 | 0.38 |
| ▸ | CBX7 | O95931 | 1/20 | 0.38 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.38 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.38 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | CTSG | P08311 | 1/20 | 0.37 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.37 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.36 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.35 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15786402 | 0.80 | SLC9A1 (0.58) | SLC9A1ALDH1A1SMN1; SMN2ELANEPRTN3 | |
| SCHEMBL13091045 | 0.80 | SLC9A1 (0.58) | SLC9A1ALDH1A1SMN1; SMN2ELANEPRTN3 | |
| SCHEMBL13340980 | 0.78 | SLC9A1 (0.57) | SLC9A1ALDH1A1PTGER3PGR | |
| SCHEMBL16362032 | 0.77 | NISCH (0.52) | ALDH1A1SMN1; SMN2NISCHELANECTSG | |
| SCHEMBL15783472 | 0.76 | SLC9A1 (0.55) | SLC9A1ALDH1A1CYP2C9PGR | |
| SCHEMBL17027045 | 0.73 | ALPL (0.49) | ALDH1A1NISCHELANECTSGPRTN3 | |
| SCHEMBL8029177 | 0.72 | SLC9A1 (0.66) | SLC9A1ALDH1A1SMN1; SMN2ELANECTSG | |
| SCHEMBL8039159 | 0.72 | SLC9A1 (0.66) | SLC9A1ALDH1A1SMN1; SMN2CYP2C9 | |
| SCHEMBL14169864 | 0.72 | XIAP (0.52) | SLC9A1XIAPALDH1A1SMN1; SMN2NISCH | |
| SCHEMBL3288905 | 0.71 | SLC9A1 (0.47) | SLC9A1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2928891-B1 | PROTEIN KINASE C INHIBITORS AND USES THEREOF | RIGEL PHARMACEUTICALS INC (US) | 2019-02-20 | — | — | EP | disclosed |