Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.40 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14729157 | 0.90 | NPC1 (0.46) | NPC1RAB9ASMN1; SMN2SRCMEN1 | |
| SCHEMBL27959986 | 0.85 | TAAR1 (0.46) | NPC1RAB9ASMN1; SMN2SRCMEN1 | |
| SCHEMBL30300608 | 0.83 | NPC1 (0.42) | NPC1RAB9ASMN1; SMN2SRCMEN1 | |
| SCHEMBL3015011 | 0.83 | SMN1; SMN2 (0.49) | NPC1RAB9ASMN1; SMN2SRCMEN1 | |
| SCHEMBL22539808 | 0.81 | P2RX7 (0.43) | SMN1; SMN2SRCMEN1KMT2AP2RX7 | |
| SCHEMBL27515511 | 0.81 | SRC (0.40) | NPC1RAB9ASMN1; SMN2SRCMEN1 | |
| SCHEMBL11217315 | 0.80 | NPSR1 (0.52) | NPC1RAB9ASMN1; SMN2SRCMEN1 | |
| SCHEMBL1257788 | 0.80 | SRC (0.62) | NPC1RAB9ASMN1; SMN2SRCMEN1 | |
| SCHEMBL1257786 | 0.80 | NPSR1 (0.45) | NPC1RAB9ASMN1; SMN2SRCMEN1 | |
| SCHEMBL4050941 | 0.80 | NPC1 (0.45) | NPC1RAB9ASMN1; SMN2SRCMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010123139-A1 | ARYLCARBOXAMIDE DERIVATIVE HAVING SULFAMOYL GROUP | 持田製薬株式会社 (JP) | 2010-10-28 | — | — | WO | disclosed |