SCHEMBL14729157

SCHEMBL14729157

Cc1ccc(CC(=O)Cc2ccc(C)cc2C)c(C)c1

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
SRC P12931 1/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
PYCR1 P32322 1/20 0.44
P2RX7 Q99572 2/20 0.43
TP53 P04637 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
PSMB5 P28074 2/20 0.42
PSMB8 P28062 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
ALDH1A1 P00352 1/20 0.42
HTT P42858 1/20 0.42
TAAR1 Q96RJ0 1/20 0.41
RXRA P19793 2/20 0.40
RXRB P28702 2/20 0.40
RXRG P48443 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13091046 0.90 NPC1 (0.43) NPC1RAB9ASRCMEN1KMT2A
SCHEMBL3015011 0.88 SMN1; SMN2 (0.49) NPC1RAB9ASRCMEN1KMT2A
SCHEMBL30300608 0.88 NPC1 (0.42) NPC1RAB9ASRCMEN1KMT2A
SCHEMBL11217315 0.85 NPSR1 (0.52) NPC1RAB9ASRCMEN1KMT2A
SCHEMBL4050941 0.85 NPC1 (0.45) NPC1RAB9ASRCMEN1KMT2A
SCHEMBL1257786 0.85 NPSR1 (0.45) NPC1RAB9ASRCMEN1KMT2A
SCHEMBL1257788 0.85 SRC (0.62) NPC1RAB9ASRCMEN1KMT2A
SCHEMBL8316865 0.84 KCNH2 (0.41) NPC1RAB9ASRCMEN1KMT2A
SCHEMBL2530247 0.83 P2RX7 (0.44) NPC1RAB9ASRCMEN1KMT2A
SCHEMBL2702114 0.83 ICMT (0.45) NPC1RAB9ASRCMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111743783-B Double-paste type dental resin reinforced glass ion water-gate composition 株式会社松风 2024-04-16 CN disclosed
US-11370733-B2 Organic compound, organic light-emitting element, display device, imaging device, electronic device, illumination device, and moving object CANON KABUSHIKI KAISHA (JP) 2022-06-28 US disclosed
US-20200048171-A1 ORGANIC COMPOUND, ORGANIC LIGHT-EMITTING ELEMENT, DISPLAY DEVICE, IMAGING DEVICE, ELECTRONIC DEVICE, ILLUMINATION DEVICE, AND MOVING OBJECT CANON KABUSHIKI KAISHA (JP) 2020-02-13 US disclosed
US-8900727-B2 Condensed polycyclic compound, organic light-emitting device having the same, display device, image information processing device, lighting device, image formation device, and exposure light source CANON KABUSHIKI KAISHA (JP) 2014-12-02 US disclosed
US-8900727-B2 Condensed polycyclic compound, organic light-emitting device having the same, display device, image information processing device, lighting device, image formation device, and exposure light source CANON KABUSHIKI KAISHA (JP) 2014-12-02 US disclosed
US-20130050561-A1 NOVEL CONDENSED POLYCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE HAVING THE SAME, DISPLAY DEVICE, IMAGE INFORMATION PROCESSING DEVICE, LIGHTING DEVICE, IMAGE FORMATION DEVICE, AND EXPOSURE LIGHT SOURCE CANON KABUSHIKI KAISHA (JP) 2013-02-28 US disclosed
US-20130050561-A1 NOVEL CONDENSED POLYCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE HAVING THE SAME, DISPLAY DEVICE, IMAGE INFORMATION PROCESSING DEVICE, LIGHTING DEVICE, IMAGE FORMATION DEVICE, AND EXPOSURE LIGHT SOURCE CANON KABUSHIKI KAISHA (JP) 2013-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200048171-A1 ORGANIC COMPOUND, ORGANIC LIGHT-EMITTING ELEMENT, DISPLAY DEVICE, IMAGING DEVICE, ELECTRONIC DEVICE, ILLUMINATION DEVICE, AND MOVING OBJECT OCIAD1, L1CAM, SPIN4 NPC1 1324/4885RAB9A 2123/4885SRC 793/4885
US-20130050561-A1 NOVEL CONDENSED POLYCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE HAVING THE SAME, DISPLAY DEVICE, IMAGE INFORMATION PROCESSING DEVICE, LIGHTING DEVICE, IMAGE FORMATION DEVICE, AND EXPOSURE LIGHT SOURCE CCND2, CCNE2, C1R NPC1 1217/4885RAB9A 787/4885SRC 3917/4885
US-11370733-B2 Organic compound, organic light-emitting element, display device, imaging device, electronic device, illumination device, and moving object OCIAD1, L1CAM, SPIN4 NPC1 1324/4885RAB9A 2123/4885SRC 793/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.