Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 9/20 | 0.38 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.38 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21505014 | 0.83 | ADRB2 (0.40) | ACHEAADATALDH1A1 | |
| SCHEMBL2733639 | 0.82 | TRPV1 (0.49) | TRPV1 | |
| SCHEMBL2733666 | 0.82 | TRPV1 (0.49) | TRPV1 | |
| SCHEMBL2734503 | 0.82 | TRPV1 (0.49) | TRPV1 | |
| SCHEMBL30864984 | 0.78 | ACHE (0.46) | ACHEAADAT | |
| SCHEMBL27500043 | 0.78 | ACHE (0.46) | ACHEAADAT | |
| SCHEMBL12540413 | 0.75 | SLC18A3 (0.48) | TRPV1 | |
| SCHEMBL287202 | 0.75 | SLC18A3 (0.48) | TRPV1 | |
| SCHEMBL9455952 | 0.75 | TRPV1 (0.38) | TRPV1 | |
| SCHEMBL31278528 | 0.75 | DRD2 (0.46) | ACHEAADAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010123139-A1 | ARYLCARBOXAMIDE DERIVATIVE HAVING SULFAMOYL GROUP | 持田製薬株式会社 (JP) | 2010-10-28 | — | — | WO | disclosed |