Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
| ▸ | DAO | P14920 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13092524 | 0.74 | GFER (0.52) | — | |
| SCHEMBL7239671 | 0.72 | TAAR1 (0.54) | ADRA2BTAAR1 | |
| SCHEMBL9872869 | 0.72 | MAOA (0.53) | — | |
| SCHEMBL26460682 | 0.70 | ADRA2B (0.47) | ADRA2BTAAR1 | |
| SCHEMBL1488954 | 0.70 | — | — | |
| SCHEMBL4671779 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL9928911 | 0.68 | HRH2 (0.31) | — | |
| Hydrochloric Acid SCHEMBL1949038 | 0.68 | — | — | |
| SCHEMBL9057541 | 0.68 | MAOB (0.44) | DAO | |
| SCHEMBL23413275 | 0.68 | ADRA2B (0.45) | ADRA2BTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010123017-A1 | TETRAZOLE COMPOUND | アステラス製薬株式会社 (JP) | 2010-10-28 | — | — | WO | disclosed |