Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.44 |
| ▸ | GFER | P55789 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13092524 | 0.89 | GFER (0.52) | MAOBGFERMAOATSHRTDP1 | |
| SCHEMBL5026313 | 0.83 | IGF1R (0.39) | MAOBALDH1A1DAOL3MBTL1 | |
| SCHEMBL7819517 | 0.82 | DAO (0.50) | MAOBMAOASIGMAR1HTR2ADAO | |
| Hydrochloric Acid SCHEMBL5039722 | 0.81 | IGF1R (0.38) | GFERTDP1ALDH1A1DAODRD2 | |
| SCHEMBL4573094 | 0.80 | CYP3A4 (0.48) | MAOBGFERMAOATSHRTDP1 | |
| SCHEMBL5176963 | 0.79 | ESR1 (0.46) | ALDH1A1CYP3A4HTR1ATP53KDM4E | |
| SCHEMBL3872946 | 0.79 | ALDH1A1 (0.33) | ALDH1A1L3MBTL1 | |
| SCHEMBL15599121 | 0.76 | SIGMAR1 (0.47) | SIGMAR1KMT2A | |
| SCHEMBL2705361 | 0.74 | L3MBTL1 (0.32) | L3MBTL1 | |
| SCHEMBL12110702 | 0.74 | GFER (0.77) | MAOBGFERMAOASIGMAR1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996004246-A1 | PHENYLACETAMIDES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION | LABORATORIOS MENARINI S.A. (ES) | 1996-02-15 | — | — | WO | disclosed |