Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 2/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13093181 | 0.89 | NTRK1 (0.40) | PDE4BNTRK1USP30NR1H2NR1H3 | |
| SCHEMBL13093170 | 0.84 | SLC6A4 (0.55) | — | |
| SCHEMBL13092975 | 0.84 | SLC6A4 (0.55) | — | |
| SCHEMBL13093283 | 0.84 | SLC6A4 (0.55) | — | |
| SCHEMBL13093189 | 0.84 | SLC6A4 (0.55) | — | |
| SCHEMBL20806008 | 0.84 | PDE4B (0.42) | PDE4BALDH1A1 | |
| SCHEMBL5973789 | 0.84 | PDE4B (0.42) | PDE4BALDH1A1 | |
| SCHEMBL7436099 | 0.84 | PDE4B (0.42) | PDE4BALDH1A1 | |
| SCHEMBL15185061 | 0.83 | ALDH1A1 (0.50) | PDE4BALDH1A1 | |
| SCHEMBL16732450 | 0.82 | SLC6A3 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010123006-A1 | PYRROLIDINE COMPOUND | 武田薬品工業株式会社 (JP) | 2010-10-28 | — | — | WO | disclosed |