Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 3/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13093185 | 0.89 | PDE4B (0.43) | NTRK1DPP4GRM5USP30NR1H2 | |
| SCHEMBL23013151 | 0.88 | TACR1 (0.43) | NTRK1HSD17B10DPP4USP30NR1H2 | |
| SCHEMBL29481460 | 0.88 | TACR1 (0.43) | NTRK1HSD17B10DPP4USP30NR1H2 | |
| SCHEMBL16733050 | 0.87 | TACR1 (0.43) | HSD17B10GRM5MMP13RORC | |
| SCHEMBL16732985 | 0.87 | TACR1 (0.43) | HSD17B10GRM5MMP13RORC | |
| SCHEMBL15185124 | 0.85 | RIPK1 (0.49) | GRM5NR1H2NR1H3RORC | |
| SCHEMBL13092909 | 0.84 | SLC6A4 (0.46) | GRM5ALDH1A1 | |
| SCHEMBL13092908 | 0.84 | SLC6A4 (0.46) | GRM5ALDH1A1 | |
| SCHEMBL13093494 | 0.84 | SLC6A4 (0.46) | GRM5ALDH1A1 | |
| SCHEMBL7475696 | 0.83 | RORC (0.40) | HSD17B10GRM5PDE4BRORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010123006-A1 | PYRROLIDINE COMPOUND | 武田薬品工業株式会社 (JP) | 2010-10-28 | — | — | WO | disclosed |