SCHEMBL1309504

SCHEMBL1309504

Cc1c(N)ccc(N=Cc2cccc([N+](=O)[O-])c2)c1C

nearest known ligand 0.53

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ PTGS2 P35354 1/20 0.53
▸ MEN1 O00255 3/20 0.52
▸ KMT2A Q03164 3/20 0.52
▸ ALDH1A1 P00352 5/20 0.51
▸ KDM4E B2RXH2 1/20 0.51
▸ POLB P06746 1/20 0.48
▸ NFE2L2 Q16236 2/20 0.48
▸ MAOB P27338 1/20 0.47
▸ HPGD P15428 2/20 0.47
▸ LMNA P02545 1/20 0.47
▸ AMY1A P0DUB6 1/20 0.47
▸ HTT P42858 1/20 0.47
▸ SMN1; SMN2 Q16637 1/20 0.46
▸ FBP1 P09467 1/20 0.44
▸ VCP P55072 1/20 0.44
▸ CYP19A1 P11511 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9174287 0.84 MEN1 (0.55) PTGS2MEN1KMT2AALDH1A1KDM4E
SCHEMBL9169373 0.78 PTGS2 (0.61) PTGS2MEN1KMT2AALDH1A1KDM4E
SCHEMBL9174473 0.77 NFE2L2 (0.56) PTGS2MEN1KMT2AALDH1A1KDM4E
SCHEMBL22624828 0.75 CDK2 (0.56) PTGS2MEN1KMT2AALDH1A1KDM4E
SCHEMBL28964185 0.75 PTGS2 (0.69) PTGS2MEN1KMT2AALDH1A1KDM4E
SCHEMBL6430523 0.75 PTGS2 (0.73) PTGS2MEN1KMT2AALDH1A1KDM4E
SCHEMBL5790069 0.75 PTGS2 (0.73) PTGS2MEN1KMT2AALDH1A1KDM4E
SCHEMBL30301287 0.75 PTGS2 (0.69) PTGS2MEN1KMT2AALDH1A1KDM4E
SCHEMBL2136470 0.75 PTGS2 (0.69) PTGS2MEN1KMT2AALDH1A1KDM4E
SCHEMBL15312914 0.74 MEN1 (0.60) PTGS2MEN1KMT2AALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8470633-B2 Circuit architecture on an organic base and related manufacturing method STMICROELECTRONICS S.R.L. (IT) 2013-06-25 — — US disclosed
US-20110275018-A1 CIRCUIT ARCHITECTURE ON AN ORGANIC BASE AND RELATED MANUFACTURING METHOD STMICROELECTRONICS S.R.L. (IT) 2011-11-10 — — US disclosed
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