SCHEMBL9174287

SCHEMBL9174287

Cc1cccc(N=Cc2cccc([N+](=O)[O-])c2)c1C

nearest known ligand 0.55

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 3/20 0.55
▸ KMT2A Q03164 3/20 0.55
▸ ALDH1A1 P00352 4/20 0.53
▸ KDM4E B2RXH2 1/20 0.53
▸ PTGS2 P35354 1/20 0.52
▸ HPGD P15428 3/20 0.50
▸ NFE2L2 Q16236 2/20 0.50
▸ SMN1; SMN2 Q16637 1/20 0.50
▸ POLB P06746 1/20 0.50
▸ MAOB P27338 1/20 0.49
▸ LMNA P02545 1/20 0.49
▸ AMY1A P0DUB6 1/20 0.49
▸ HTT P42858 1/20 0.49
▸ MAPT P10636 1/20 0.48
▸ FBP1 P09467 1/20 0.47
▸ VCP P55072 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9175025 0.86 ALDH1A1 (0.56) MEN1KMT2AALDH1A1KDM4EPTGS2
SCHEMBL1309504 0.84 PTGS2 (0.53) MEN1KMT2AALDH1A1KDM4EPTGS2
SCHEMBL9174473 0.82 NFE2L2 (0.56) MEN1KMT2AALDH1A1KDM4EPTGS2
SCHEMBL9169373 0.80 PTGS2 (0.61) MEN1KMT2AALDH1A1KDM4EPTGS2
SCHEMBL10118539 0.79 MEN1 (0.60) MEN1KMT2AALDH1A1KDM4EPTGS2
SCHEMBL15312914 0.79 MEN1 (0.60) MEN1KMT2AALDH1A1KDM4EPTGS2
SCHEMBL27912400 0.78 KMT2A (0.58) MEN1KMT2AALDH1A1KDM4EPTGS2
SCHEMBL22624828 0.77 CDK2 (0.56) MEN1KMT2AALDH1A1KDM4EPTGS2
SCHEMBL28964185 0.77 PTGS2 (0.69) MEN1KMT2AALDH1A1KDM4EPTGS2
SCHEMBL30301287 0.77 PTGS2 (0.69) MEN1KMT2AALDH1A1KDM4EPTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0473140-B1 Method of forming thin film on fiber end surface SUMITOMO ELECTRIC INDUSTRIES (JP) 1995-11-15 — — EP claimed
EP-0424689-B1 Fiber-type wavelenghth converting device SUMITOMO ELECTRIC INDUSTRIES (JP) 1995-09-13 — — EP disclosed
US-5385116-A Method for producing organic crystal film SUMITOMO ELECTRIC INDUSTRIES, LTD. (JP) 1995-01-31 — — US disclosed
US-5323261-A Harmonic generating device SUMITOMO ELECTRIC INDUSTRIES, LTD. (JP) 1994-06-21 — — US disclosed
EP-0562587-A1 Method for producing organic crystal film SUMITOMO ELECTRIC INDUSTRIES, LTD. (JP) 1993-09-29 — — EP disclosed
US-5022738-A Optical fiber nonlinear wavelength modulator device SUMITOMO ELECTRIC INDUSTRIES, LTD. (JP) 1991-06-11 — — US disclosed
EP-0424689-A2 Fiber-type wavelenghth converting device SUMITOMO ELECTRIC INDUSTRIES, LTD. (JP) 1991-05-02 — — EP disclosed
EP-0420156-A1 Wavelength modulator device SUMITOMO ELECTRIC INDUSTRIES, LTD. (JP) 1991-04-03 — — EP disclosed
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