Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 19/20 | 0.60 |
| ▸ | MTNR1B | P49286 | 19/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.50 |
| ▸ | HTR2B | P41595 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | THPO | P40225 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | NQO2 | P16083 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1309396 | 0.81 | MTNR1A (0.67) | MTNR1AMTNR1BCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7893103 | 0.77 | MTNR1A (0.69) | MTNR1AMTNR1BCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL31543622 | 0.72 | MTNR1A (0.67) | MTNR1AMTNR1BCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3221539 | 0.72 | MTNR1A (0.74) | MTNR1AMTNR1BCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL10907993 | 0.72 | MTNR1A (0.76) | MTNR1AMTNR1BCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL10905707 | 0.71 | MTNR1A (0.65) | MTNR1AMTNR1BCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL1309627 | 0.71 | MTNR1A (0.64) | MTNR1AMTNR1BCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL31543668 | 0.69 | MTNR1A (0.60) | MTNR1AMTNR1BCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL1310438 | 0.69 | MTNR1A (0.40) | MTNR1AMTNR1BCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL25236273 | 0.68 | MTNR1A (1.00) | MTNR1AMTNR1BCYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8053462-B2 | Indole derivative and application thereof | SOMEI MASANORI | 2011-11-08 | — | — | US | disclosed |
| US-8053462-B2 | Indole derivative and application thereof | SOMEI MASANORI | 2011-11-08 | — | — | US | disclosed |
| US-8053462-B2 | Indole derivative and application thereof | SOMEI MASANORI | 2011-11-08 | — | — | US | disclosed |
| US-20070197629-A1 | Indole derivative and application thereof | SOMEI MASANORI | 2007-08-23 | — | — | US | disclosed |
| US-20070197629-A1 | Indole derivative and application thereof | SOMEI MASANORI | 2007-08-23 | — | — | US | disclosed |
| US-20070197629-A1 | Indole derivative and application thereof | SOMEI MASANORI | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197629-A1 | Indole derivative and application thereof | ARL1, IDO1, AIPL1 | MTNR1A 143/4885MTNR1B 287/4885CYP1A2 2752/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.