SCHEMBL1309519

SCHEMBL1309519

CCN(CC)c1ccc(/N=N/c2ccc([N+](=O)[O-])cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 11/20 0.56
L3MBTL1 Q9Y468 5/20 0.56
RAB9A P51151 5/20 0.56
MAPK1 P28482 4/20 0.56
SMN1; SMN2 Q16637 4/20 0.56
NPC1 O15118 4/20 0.56
TDP1 Q9NUW8 3/20 0.56
ALPL P05186 1/20 0.56
ALPI P09923 1/20 0.56
ALPG P10696 1/20 0.56
NFKB1 P19838 1/20 0.56
NFKB2 Q00653 1/20 0.56
RELA Q04206 1/20 0.56
MMP14 P50281 1/20 0.53
ALDH1A1 P00352 10/20 0.52
MEN1 O00255 9/20 0.52
KMT2A Q03164 9/20 0.52
TNNI3 P19429 1/20 0.51
TNNT2 P45379 1/20 0.51
TNNC1 P63316 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1309521 1.00 MAPT (0.56) MAPTL3MBTL1RAB9AMAPK1SMN1; SMN2
SCHEMBL4409817 0.91 MAPT (0.49) MAPTL3MBTL1RAB9AMAPK1SMN1; SMN2
SCHEMBL17787276 0.91 MMP14 (0.52) MAPTL3MBTL1RAB9AMAPK1SMN1; SMN2
SCHEMBL4409819 0.91 MAPT (0.49) MAPTL3MBTL1RAB9AMAPK1SMN1; SMN2
SCHEMBL15827083 0.91 MMP14 (0.52) MAPTL3MBTL1RAB9AMAPK1SMN1; SMN2
SCHEMBL160430 0.89 ALDH1A1 (0.57) MAPTL3MBTL1RAB9AMAPK1TDP1
SCHEMBL532332 0.88 MAPT (0.59) MAPTL3MBTL1RAB9AMAPK1SMN1; SMN2
SCHEMBL2314232 0.88 MMP14 (0.50) MAPTL3MBTL1RAB9AMAPK1SMN1; SMN2
SCHEMBL2314229 0.88 MMP14 (0.50) MAPTL3MBTL1RAB9AMAPK1SMN1; SMN2
SCHEMBL148266 0.88 MAPT (0.59) MAPTL3MBTL1RAB9AMAPK1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1991009842-A1 ELECTRO-OPTICAL MATERIALS AND LIGHT MODULATOR DEVICES CONTAINING SAME ALLIED-SIGNAL INC. (US) 1991-07-11 WO claimed
US-9575246-B2 Prepolymer, curable material, coating composition, non-linear optical material, optical waveguide and light control device ASAHI GLASS COMPANY, LIMITED (JP) 2017-02-21 US disclosed
EP-2276798-B1 METHOD FOR CROSSLINKING BY THERMAL HUISGEN REACTION, CROSSLINKABLE CHROMOPHORIC POLYMERS, AND CROSSLINKED POLYMER SUBSTANCES HAVING STABLE ELECTRO-OPTICAL PROPERTIES CENTRE NAT DE LA RECH SCIENT (C N R S ) (FR) 2017-02-01 EP disclosed
EP-2889684-A1 PREPOLYMER, CURABLE MATERIAL, COATING COMPOSITION, NON-LINEAR OPTICAL MATERIAL, OPTICAL WAVEGUIDE AND LIGHT CONTROL DEVICE Asahi Glass Company, Limited (JP) 2015-07-01 EP disclosed
US-20150153509-A1 PREPOLYMER, CURABLE MATERIAL, COATING COMPOSITION, NON-LINEAR OPTICAL MATERIAL, OPTICAL WAVEGUIDE AND LIGHT CONTROL DEVICE ASAHI GLASS COMPANY, LIMITED (JP) 2015-06-04 US disclosed
EP-1606354-B1 POLYMERIZABLE DICHROIC AZO DYES ROLIC AG (CH) 2012-05-30 EP disclosed
WO-2012019704-A1 PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GMBH (DE) 2012-02-16 WO disclosed
US-8053039-B2 Polymerizable dichroic azo dyes ROLIC AG (CH) 2011-11-08 US disclosed
US-20110065864-A1 Method for Crosslinking by Thermal Huisgen Reaction, Crosslinkable Chromophoric Polymers, and Crosslinked Polymer Substances Having Stable Electro-Optical Properties CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2011-03-17 US disclosed
WO-2009138643-A1 METHOD FOR CROSSLINKING BY THERMAL HUISGEN REACTION, CROSSLINKABLE CHROMOPHORIC POLYMERS, AND CROSSLINKED POLYMER SUBSTANCES HAVING STABLE ELECTRO-OPTICAL PROPERTIES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS - (FR) 2009-11-19 WO disclosed
US-20060188663-A1 Polymerizable dichroic azo dyes ROLIC AG (CH) 2006-08-24 US disclosed
EP-1462485-A1 Polymerizable dichroic azo dyes Rolic AG (CH) 2004-09-29 EP disclosed
EP-0567379-B1 Photochemically crosslinked material for non-linear optical application THOMSON CSF (FR) 1997-07-23 EP disclosed
US-5332521-A Ferroelectric liquid crystal composition, liquid crystal optical device produced by using the ferroelectric liquid crystal composition, and method of producing the liquid crystal optical device IDEMITSU KOSAN CO., LTD. (JP) 1994-07-26 US disclosed
EP-0352637-B1 Ferroelectric liquid crystal composition, liquid crystal optical device produced by using the ferroelectric liquid crystal composition, and method of producing the liquid crystal optical device IDEMITSU KOSAN CO (JP) 1994-03-30 EP disclosed
EP-0567379-A1 Photochemically crosslinked material for non-linear optical application THOMSON-CSF (FR) 1993-10-27 EP disclosed
US-5200108-A Flexible substrates supporting layer of liquid crystal material and non-liquid crystalline polymer IDEMITSU KOSAN CO., LTD. (JP) 1993-04-06 US disclosed
EP-0352637-A2 Ferroelectric liquid crystal composition, liquid crystal optical device produced by using the ferroelectric liquid crystal composition, and method of producing the liquid crystal optical device IDEMITSU KOSAN COMPANY LIMITED (JP) 1990-01-31 EP disclosed