Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP14 | P50281 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 8/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | ALPL | P05186 | 1/20 | 0.47 |
| ▸ | ALPI | P09923 | 1/20 | 0.47 |
| ▸ | ALPG | P10696 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 6/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2314229 | 1.00 | MMP14 (0.50) | MMP14MAPTL3MBTL1MAPK1NPC1 | |
| SCHEMBL15827083 | 0.89 | MMP14 (0.52) | MMP14MAPTL3MBTL1MAPK1NPC1 | |
| SCHEMBL17787276 | 0.89 | MMP14 (0.52) | MMP14MAPTL3MBTL1MAPK1NPC1 | |
| SCHEMBL1309519 | 0.88 | MAPT (0.56) | MMP14MAPTL3MBTL1MAPK1NPC1 | |
| SCHEMBL1309521 | 0.88 | MAPT (0.56) | MMP14MAPTL3MBTL1MAPK1NPC1 | |
| SCHEMBL148266 | 0.86 | MAPT (0.59) | MMP14MAPTL3MBTL1MAPK1NPC1 | |
| SCHEMBL532332 | 0.86 | MAPT (0.59) | MMP14MAPTL3MBTL1MAPK1NPC1 | |
| SCHEMBL9219535 | 0.84 | MAPT (0.40) | MMP14MAPTL3MBTL1MAPK1NPC1 | |
| SCHEMBL18556762 | 0.84 | MMP14 (0.48) | MMP14MAPTL3MBTL1MAPK1NPC1 | |
| SCHEMBL19472266 | 0.84 | MMP14 (0.48) | MMP14MAPTL3MBTL1MAPK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1855643-B1 | DYEING OF IN PARTICULAR HUMAN KERATIN MATERIALS BY DRY THERMAL TRANSFER OF A DIRECT DYE, COMPOSITION COMPRISING THE SAID DYE AND ITS METHOD OF PREPARATION | OREAL (FR) | 2011-08-03 | — | — | EP | claimed |
| US-7722680-B2 | Dyeing of human keratin materials by dry thermal transfer of a direct dye, composition comprising the said dye and its method of preparation | L'OREAL S.A. (FR) | 2010-05-25 | — | — | US | claimed |
| US-7611545-B2 | Cosmetic article and process for dry dyeing keratin materials | L'OREAL S.A. (FR) | 2009-11-03 | — | — | US | claimed |
| US-20080244837-A1 | Cosmetic article and process for dry dyeing keratin materials | L'OREAL S.A. (FR) | 2008-10-09 | — | — | US | claimed |
| EP-1964539-A1 | Cosmetic article for dyeing dry hair, its use, method of implementing said article | L'Oréal (FR) | 2008-09-03 | — | — | EP | claimed |
| US-20080148496-A1 | Dyeing of in Particular Human Keratin Materials by Dry Thermal Transfer of a Direct Dye, Composition Comprising the Said Dye and Its Method of Preparation | L'OREAL S.A. (FR) | 2008-06-26 | — | — | US | claimed |
| EP-1855643-B1 | DYEING OF IN PARTICULAR HUMAN KERATIN MATERIALS BY DRY THERMAL TRANSFER OF A DIRECT DYE, COMPOSITION COMPRISING THE SAID DYE AND ITS METHOD OF PREPARATION | OREAL (FR) | 2011-08-03 | — | — | EP | disclosed |
| US-7722680-B2 | Dyeing of human keratin materials by dry thermal transfer of a direct dye, composition comprising the said dye and its method of preparation | L'OREAL S.A. (FR) | 2010-05-25 | — | — | US | disclosed |
| US-7722680-B2 | Dyeing of human keratin materials by dry thermal transfer of a direct dye, composition comprising the said dye and its method of preparation | L'OREAL S.A. (FR) | 2010-05-25 | — | — | US | disclosed |
| US-7722680-B2 | Dyeing of human keratin materials by dry thermal transfer of a direct dye, composition comprising the said dye and its method of preparation | L'OREAL S.A. (FR) | 2010-05-25 | — | — | US | disclosed |
| US-7611545-B2 | Cosmetic article and process for dry dyeing keratin materials | L'OREAL S.A. (FR) | 2009-11-03 | — | — | US | disclosed |
| US-20080244837-A1 | Cosmetic article and process for dry dyeing keratin materials | L'OREAL S.A. (FR) | 2008-10-09 | — | — | US | disclosed |
| EP-1964539-A1 | Cosmetic article for dyeing dry hair, its use, method of implementing said article | L'Oréal (FR) | 2008-09-03 | — | — | EP | disclosed |
| US-20080148496-A1 | Dyeing of in Particular Human Keratin Materials by Dry Thermal Transfer of a Direct Dye, Composition Comprising the Said Dye and Its Method of Preparation | L'OREAL S.A. (FR) | 2008-06-26 | — | — | US | disclosed |
| US-20080148496-A1 | Dyeing of in Particular Human Keratin Materials by Dry Thermal Transfer of a Direct Dye, Composition Comprising the Said Dye and Its Method of Preparation | L'OREAL S.A. (FR) | 2008-06-26 | — | — | US | disclosed |
| US-20080148496-A1 | Dyeing of in Particular Human Keratin Materials by Dry Thermal Transfer of a Direct Dye, Composition Comprising the Said Dye and Its Method of Preparation | L'OREAL S.A. (FR) | 2008-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080244837-A1 | Cosmetic article and process for dry dyeing keratin materials | KRT18, CUTA, DSG1 | MMP14 874/4885MAPT 559/4885L3MBTL1 4716/4885 |
| US-20080148496-A1 | Dyeing of in Particular Human Keratin Materials by Dry Thermal Transfer of a Direct Dye, Composition Comprising the Said Dye and Its Method of Preparation | KRT18, IK, DSG1 | MMP14 1991/4885MAPT 275/4885L3MBTL1 4854/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.