SCHEMBL1309596

SCHEMBL1309596

Cc1c(C)c(-c2ccc(-c3ccccc3)cc2)c(C)c(C)c1B(c1c(C)c(C)c(-c2ccc(-c3ccccc3)cc2)c(C)c1C)c1c(C)c(C)c(-c2ccc(-c3ccccc3)cc2)c(C)c1C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.39
MAPT P10636 3/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
MGLL Q99685 1/20 0.37
CYP1A2 P05177 2/20 0.36
LMNA P02545 2/20 0.36
HTT P42858 2/20 0.36
MAPK1 P28482 1/20 0.36
CYP3A4 P08684 1/20 0.36
TAAR1 Q96RJ0 1/20 0.36
HSD17B10 Q99714 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
MMP3 P08254 1/20 0.36
BCL2L1 Q07817 1/20 0.36
SENP1 Q9P0U3 1/20 0.35
CHEK1 O14757 1/20 0.35
AKT2 P31751 1/20 0.35
BRD4 O60885 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1311706 0.96 MAPT (0.39) ALDH1A1MAPTSMN1; SMN2LMNAHTT
SCHEMBL20051845 0.90 CA1 (0.42) ALDH1A1MAPTSMN1; SMN2CA1CA2
SCHEMBL10100965 0.90 CA1 (0.42) ALDH1A1MAPTSMN1; SMN2CA1CA2
SCHEMBL17249483 0.88 CA1 (0.41) ALDH1A1MAPTSMN1; SMN2CA1CA2
SCHEMBL1309858 0.88 PTGS1 (0.38) ALDH1A1MAPTSMN1; SMN2CA1CA2
SCHEMBL9701635 0.81 LMNA (0.50) ALDH1A1MAPTLMNAHTTHSD17B10
SCHEMBL12110557 0.80 ESR2 (0.40) ALDH1A1MAPTLMNAL3MBTL1PTGS1
SCHEMBL13866713 0.78 ACHE (0.39) BCL2L1SENP1PTGS1PTGS2
SCHEMBL8618279 0.78 LMNA (0.48) ALDH1A1MAPTLMNAHTTHSD17B10
SCHEMBL17069702 0.78 RXRA (0.48) ALDH1A1SMN1; SMN2CA1CA2HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100221649-A1 BORON CONTAINING HOLE BLOCKING LAYER PHOTOCONDUCTOR XEROX CORPORATION (US) 2010-09-02 US claimed
US-7670738-B2 Boron containing photoconductors XEROX CORPORATION (US) 2010-03-02 US claimed
US-20090061338-A1 BORON CONTAINING PHOTOCONDUCTORS XEROX CORPORATION (US) 2009-03-05 US claimed
US-20140302636-A1 METHOD FOR PRODUCING A MULTI-BRANCHED STRUCTURE COMPOUND ENCAPSULATING AN IRIDIUM PHOSPHORESCENT COMPOUND KONICA MINOLTA HOLDINGS, INC. (JP) 2014-10-09 US disclosed
US-20140302636-A1 METHOD FOR PRODUCING A MULTI-BRANCHED STRUCTURE COMPOUND ENCAPSULATING AN IRIDIUM PHOSPHORESCENT COMPOUND KONICA MINOLTA HOLDINGS, INC. (JP) 2014-10-09 US disclosed
US-8053152-B2 Boron containing hole blocking layer photoconductor XEROX CORPORATION (US) 2011-11-08 US disclosed
US-8053152-B2 Boron containing hole blocking layer photoconductor XEROX CORPORATION (US) 2011-11-08 US disclosed
US-8053152-B2 Boron containing hole blocking layer photoconductor XEROX CORPORATION (US) 2011-11-08 US disclosed
US-7914962-B2 Light stabilizer containing photoconductors XEROX CORPORATION (US) 2011-03-29 US disclosed
US-7914962-B2 Light stabilizer containing photoconductors XEROX CORPORATION (US) 2011-03-29 US disclosed
US-7906224-B2 Organic electroluminescent device, display, and illuminating device KONICA MINOLTA HOLDINGS, INC. (JP) 2011-03-15 US disclosed
US-20090061337-A1 PHOTOCONDUCTORS XEROX CORPORATION (US) 2009-03-05 US disclosed
US-20090061337-A1 PHOTOCONDUCTORS XEROX CORPORATION (US) 2009-03-05 US disclosed
US-20090061337-A1 PHOTOCONDUCTORS XEROX CORPORATION (US) 2009-03-05 US disclosed
US-20090061336-A1 LIGHT STABILIZER CONTAINING PHOTOCONDUCTORS XEROX CORPORATION (US) 2009-03-05 US disclosed
US-20090061336-A1 LIGHT STABILIZER CONTAINING PHOTOCONDUCTORS XEROX CORPORATION (US) 2009-03-05 US disclosed
US-20090061338-A1 BORON CONTAINING PHOTOCONDUCTORS XEROX CORPORATION (US) 2009-03-05 US disclosed
US-20090061338-A1 BORON CONTAINING PHOTOCONDUCTORS XEROX CORPORATION (US) 2009-03-05 US disclosed
US-20070207340-A1 Compound of Multi-Branched Structure, Organic Electroluminescent Element, Display, Illuminating Device, and Method for Producing Compound of Multi-Branched Structure KONICA MINOLTA HOLDINGS, INC. (JP) 2007-09-06 US disclosed
US-20070207340-A1 Compound of Multi-Branched Structure, Organic Electroluminescent Element, Display, Illuminating Device, and Method for Producing Compound of Multi-Branched Structure KONICA MINOLTA HOLDINGS, INC. (JP) 2007-09-06 US disclosed