Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 5/20 | 0.40 |
| ▸ | DYRK1B | Q9Y463 | 4/20 | 0.40 |
| ▸ | CLK1 | P49759 | 4/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.40 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.40 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4764332 | 0.71 | DYRK1A (0.44) | NPC1RAB9APIM1AKR1B1PIM2 | |
| SCHEMBL4764335 | 0.71 | DYRK1A (0.44) | NPC1RAB9APIM1AKR1B1PIM2 | |
| SCHEMBL9472495 | 0.66 | METAP1 (0.49) | NPC1RAB9APIM1AKR1B1PIM2 | |
| SCHEMBL28494165 | 0.64 | DYRK1A (0.57) | NPC1RAB9APIM1AKR1B1PIM2 | |
| SCHEMBL3126492 | 0.62 | DYRK1A (0.50) | NPC1RAB9APIM1AKR1B1PIM2 | |
| SCHEMBL3126497 | 0.62 | DYRK1A (0.50) | NPC1RAB9APIM1AKR1B1PIM2 | |
| SCHEMBL12977432 | 0.61 | ACHE (0.50) | DYRK1ADYRK1BMAPTPOLB | |
| SCHEMBL12977427 | 0.61 | ACHE (0.50) | DYRK1ADYRK1BMAPTPOLB | |
| SCHEMBL24516489 | 0.61 | DDB1 (0.49) | NPC1RAB9AHPGDMAPTKMT2A | |
| SCHEMBL7839983 | 0.60 | DYRK1A (0.49) | NPC1RAB9APIM1AKR1B1PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2238967-A2 | Skin treatment fighting skin aging II | Henkel AG & Co. KGaA (DE) | 2010-10-13 | — | — | EP | disclosed |