Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.49 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24516481 | 0.80 | DDB1 (0.54) | DDB1CRBNALDH1A1CYP19A1KMT2A | |
| SCHEMBL10938257 | 0.79 | CYP19A1 (0.40) | ALDH1A1CYP19A1KMT2AMEN1MAPT | |
| SCHEMBL10514876 | 0.76 | DDB1 (0.51) | DDB1CRBNALDH1A1CYP19A1MAP2K3 | |
| SCHEMBL24516482 | 0.75 | SLC6A2 (0.42) | ALDH1A1SMN1; SMN2KMT2AMEN1MAPK1 | |
| SCHEMBL10938628 | 0.74 | MAPT (0.43) | DDB1CRBNCYP19A1KMT2AMAPK1 | |
| SCHEMBL14665734 | 0.72 | MAOA (0.58) | DDB1CRBNALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL428339 | 0.71 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2KMT2AMEN1MAPK1 | |
| SCHEMBL24516525 | 0.70 | SLC6A4 (0.46) | MMP13 | |
| SCHEMBL11637205 | 0.69 | DDB1 (0.55) | DDB1CRBNALDH1A1CYP19A1MAP2K3 | |
| SCHEMBL1515026 | 0.69 | DRD2 (0.59) | ALDH1A1SMN1; SMN2KMT2AMEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022122975-A1 | CYCLOPENTENONES DERIVATIVES AND THEIR USE AS ANTIBIOTICS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2022-06-16 | — | — | WO | disclosed |