Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 3/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13107072 | 0.88 | EGFR (0.36) | L3MBTL1EGFRMAPTSMN1; SMN2 | |
| SCHEMBL13096699 | 0.84 | EGFR (0.47) | L3MBTL1HRH4EGFRPDE5AMAPT | |
| SCHEMBL3100912 | 0.84 | L3MBTL1 (0.42) | L3MBTL1HRH4EGFRPDE5AMAPT | |
| SCHEMBL3092175 | 0.82 | ALDH1A1 (0.43) | L3MBTL1EGFRPDE5AMAPTTDP1 | |
| SCHEMBL3092171 | 0.82 | ALDH1A1 (0.43) | L3MBTL1EGFRPDE5AMAPTTDP1 | |
| SCHEMBL3086837 | 0.82 | L3MBTL1 (0.43) | L3MBTL1HRH4EGFRPDE5AMAPT | |
| SCHEMBL3086836 | 0.82 | L3MBTL1 (0.43) | L3MBTL1HRH4EGFRPDE5AMAPT | |
| SCHEMBL13096799 | 0.81 | STAT3 (0.38) | L3MBTL1HRH4PDE5AMAPTTDP1 | |
| SCHEMBL13096723 | 0.81 | MAOB (0.46) | L3MBTL1EGFRMAPTHTTSMN1; SMN2 | |
| SCHEMBL13096851 | 0.80 | STAT3 (0.37) | L3MBTL1HRH4PDE5AMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8367702-B2 | Quinolone derivative | ASTELLAS PHARMA INC. (JP) | 2013-02-05 | — | — | US | disclosed |
| US-20100256113-A1 | QUINOLONE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2010-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256113-A1 | QUINOLONE DERIVATIVE | NQO1, NQO2, NADK | L3MBTL1 2056/4885HRH4 1218/4885EGFR 4831/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.