Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3086836 | 1.00 | L3MBTL1 (0.43) | L3MBTL1PDE5AHRH4MAPTTDP1 | |
| SCHEMBL13096693 | 0.91 | L3MBTL1 (0.40) | L3MBTL1PDE5AHRH4MAPTTDP1 | |
| SCHEMBL3100912 | 0.85 | L3MBTL1 (0.42) | L3MBTL1PDE5AHRH4MAPTTDP1 | |
| SCHEMBL13096699 | 0.83 | EGFR (0.47) | L3MBTL1PDE5AHRH4MAPTTDP1 | |
| SCHEMBL13096834 | 0.82 | L3MBTL1 (0.38) | L3MBTL1PDE5AHRH4MAPTTDP1 | |
| SCHEMBL3092175 | 0.82 | ALDH1A1 (0.43) | L3MBTL1PDE5AMAPTTDP1STAT3 | |
| SCHEMBL3092171 | 0.82 | ALDH1A1 (0.43) | L3MBTL1PDE5AMAPTTDP1STAT3 | |
| SCHEMBL3106501 | 0.81 | L3MBTL1 (0.47) | L3MBTL1PDE5AMAPTTDP1STAT3 | |
| SCHEMBL13096723 | 0.80 | MAOB (0.46) | L3MBTL1MAPTHTTSMN1; SMN2EGFR | |
| SCHEMBL13096702 | 0.78 | SMN1; SMN2 (0.42) | L3MBTL1MAPTSTAT3HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8367702-B2 | Quinolone derivative | ASTELLAS PHARMA INC. (JP) | 2013-02-05 | — | — | US | disclosed |
| US-20100256113-A1 | QUINOLONE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2010-10-07 | — | — | US | disclosed |
| EP-2194044-A1 | QUINOLONE DERIVATIVE | Astellas Pharma Inc. (JP) | 2010-06-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256113-A1 | QUINOLONE DERIVATIVE | NQO1, NQO2, NADK | L3MBTL1 2056/4885PDE5A 2167/4885HRH4 1218/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.