Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | FYN | P06241 | 2/20 | 0.33 |
| ▸ | MMP9 | P14780 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21646153 | 0.81 | ALOX5 (0.33) | ALOX5MAOAMAOB | |
| SCHEMBL31748025 | 0.80 | ALOX5 (0.40) | ALOX5ALOX15TDP1KDM4EMAOA | |
| SCHEMBL27924285 | 0.78 | ALOX5 (0.38) | ALOX5ALDH1A1KDM4EATM | |
| SCHEMBL18534187 | 0.77 | PTPN5 (0.40) | ALOX5ALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL22180390 | 0.77 | AHR (0.47) | ALOX5ALDH1A1LMNAHPGDMAPT | |
| SCHEMBL23546577 | 0.77 | ATM (0.33) | ALOX5KDM4EMAOAMAOBATM | |
| SCHEMBL9934474 | 0.77 | MEN1 (0.41) | CA2L3MBTL1ATMCA1 | |
| SCHEMBL9934469 | 0.77 | ATM (0.34) | ALOX5MAOAMAOBATMAHR | |
| SCHEMBL5970726 | 0.77 | L3MBTL1 (0.32) | ALOX5L3MBTL1MAOAMAOBATM | |
| SCHEMBL18034345 | 0.77 | ENPP2 (0.32) | ALDH1A1KDM4EMAPTL3MBTL1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9212143-B2 | Small molecule inhibitors of protein kinases | LEVOLTA PHARMACEUTICALS, INC. (US) | 2015-12-15 | — | — | US | disclosed |
| US-20130058980-A1 | SMALL MOLECULE INHIBITORS OF PROTEIN KINASES | LEVOLTA PHARMACEUTICALS, INC. | 2013-03-07 | — | — | US | disclosed |
| US-8389525-B2 | Small molecules for inhibition of protein kinases | LEVOLTA PHARMACEUTICALS, INC. | 2013-03-05 | — | — | US | disclosed |
| WO-2011139295-A1 | SMALL MOLECULE INHIBITORS OF PROTEIN KINASES | IMC BIOTECHNOLOGY, INC. (US) | 2011-11-10 | — | — | WO | disclosed |
| US-20110275645-A1 | Small Molecules for Inhibition of Protein Kinases | LEVOLTA PHARMACEUTICALS, INC. | 2011-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130058980-A1 | SMALL MOLECULE INHIBITORS OF PROTEIN KINASES | SYK, BTK, LCK | ALOX5 4000/4885ALDH1A1 4797/4885EGFR 1178/4885 |
| US-20110275645-A1 | Small Molecules for Inhibition of Protein Kinases | MAP3K1, MAP3K20, MAP3K6 | ALOX5 4172/4885ALDH1A1 4207/4885EGFR 553/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.