SCHEMBL13097600

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10005514	0.90	AKR1C3 (0.40)	PDE3BPDE3APTGS2RPS6KA3AKR1C3
	SCHEMBL12889472	0.90	PTGS2 (0.40)	PDE3BPDE3APTGS2RPS6KA3AKR1C3
	SCHEMBL10018713	0.89	PDE3B (0.41)	PDE3BPDE3APTGS2PTGS1RPS6KA3
	SCHEMBL4567632	0.88	PDE3B (0.47)	PDE3BPDE3APTGS2PTGS1RPS6KA3
	SCHEMBL13444659	0.88	PDE3B (0.47)	PDE3BPDE3APTGS2PTGS1RPS6KA3
	SCHEMBL10013948	0.88	PTGS2 (0.47)	PDE3BPDE3APTGS2PTGS1RPS6KA3
	SCHEMBL13967517	0.88	PTGS2 (0.46)	PDE3BPDE3APTGS2PTGS1RPS6KA3
	SCHEMBL2741547	0.86	PDE3B (0.42)	PDE3BPDE3APTGS2PTGS1RPS6KA3
	SCHEMBL2741562	0.86	PDE3B (0.42)	PDE3BPDE3APTGS2PTGS1RPS6KA3
	SCHEMBL803426	0.86	PDE3B (0.48)	PDE3BPDE3APTGS2PTGS1RPS6KA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.