Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 3/20 | 0.48 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.44 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.40 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4567632 | 0.98 | PDE3B (0.47) | PDE3BPDE3APTGS2PTGS1RPS6KA3 | |
| SCHEMBL10018702 | 0.96 | PTGS2 (0.48) | PDE3BPDE3APTGS2PTGS1RPS6KA3 | |
| SCHEMBL13444659 | 0.94 | PDE3B (0.47) | PDE3BPDE3APTGS2PTGS1RPS6KA3 | |
| SCHEMBL10013948 | 0.93 | PTGS2 (0.47) | PDE3BPDE3APTGS2PTGS1RPS6KA3 | |
| SCHEMBL13967517 | 0.93 | PTGS2 (0.46) | PDE3BPDE3APTGS2PTGS1RPS6KA3 | |
| SCHEMBL2741567 | 0.92 | APP (0.46) | PDE3BPDE3APTGS2AKR1C3AKR1C2 | |
| SCHEMBL4567629 | 0.91 | PDE3B (0.48) | PDE3BPDE3APTGS2PTGS1RPS6KA3 | |
| SCHEMBL4567630 | 0.91 | PDE3B (0.50) | PDE3BPDE3APTGS2PTGS1RPS6KA3 | |
| SCHEMBL172359 | 0.89 | PDE3B (0.47) | PDE3BPDE3APTGS2PTGS1RPS6KA3 | |
| SCHEMBL12826296 | 0.89 | NFE2L2 (0.47) | PDE3BPDE3APTGS2PTGS1AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 200 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12043781-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2024-07-23 | — | — | US | disclosed |
| US-20240072425-A1 | AROMATIC ISOTHIOCYANATES | MERCK PATENT GMBH (DE) | 2024-02-29 | — | — | US | disclosed |
| US-20240072425-A1 | AROMATIC ISOTHIOCYANATES | MERCK PATENT GMBH (DE) | 2024-02-29 | — | — | US | disclosed |
| US-11834599-B2 | Aromatic isothiocyanates | MERCK PATENT GMBH (DE) | 2023-12-05 | — | — | US | disclosed |
| US-11834599-B2 | Aromatic isothiocyanates | MERCK PATENT GMBH (DE) | 2023-12-05 | — | — | US | disclosed |
| US-11781069-B2 | Liquid-crystal medium | MERCK PATENT GMBH (DE) | 2023-10-10 | — | — | US | disclosed |
| US-20230313043-A1 | OPTICAL COMPONENT | MERCK PATENT GMBH (DE) | 2023-10-05 | — | — | US | disclosed |
| US-11739265-B2 | Aromatic isothiocyanates | MERCK PATENT GMBH (DE) | 2023-08-29 | — | — | US | disclosed |
| US-11739265-B2 | Aromatic isothiocyanates | MERCK PATENT GMBH (DE) | 2023-08-29 | — | — | US | disclosed |
| US-11718791-B2 | Polymerisable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2023-08-08 | — | — | US | disclosed |
| US-7462297-B2 | Chiral dopants having a laterally alkylated phenyl structural element | MERCK PATENT GMBH (DE) | 2008-12-09 | — | — | US | disclosed |
| US-7445819-B2 | Liquid crystalline medium and liquid crystal display | MERCK PATENT GMBH (DE) | 2008-11-04 | — | — | US | disclosed |
| US-7390538-B2 | Liquid-crystal medium containing monofluoroterphenyl compounds | MERCK PATENT GMBH (DE) | 2008-06-24 | — | — | US | disclosed |
| US-20080124492-A1 | Liquid crystalline medium and liquid crystal display | MERCK PATENT GMBH | 2008-05-29 | — | — | US | disclosed |
| US-20080090026-A1 | Liquid-crystal display | MERCK PATENT GMBH | 2008-04-17 | — | — | US | disclosed |
| US-7314653-B2 | Liquid-crystal medium and electro-optical display containing same | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2008-01-01 | — | — | US | disclosed |
| US-20070237907-A1 | PHOTOSTABLE LIQUID-CRYSTALLINE MEDIUM | MANABE ATSUTAKA | 2007-10-11 | — | — | US | disclosed |
| US-20070235688-A1 | Liquid crystalline medium and liquid crystal display | MERCK PATENT GESELLSCHAFT | 2007-10-11 | — | — | US | disclosed |
| US-7211302-B2 | Photostable liquid crystalline medium | MERCK PATENT GMBH (DE) | 2007-05-01 | — | — | US | disclosed |
| US-20070034829-A1 | liquid crystalline medium comprises at least one strongly polar two-ring compound containing at least one fluorine group and two benezne rings; liquid-crystalline medium has a dielectric relaxation frequency of more than 200 kHz at a temperature of 0 degrees C.; use in active matrix displays | MERCK PATENT GMBH (DE) | 2007-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11718791-B2 | Polymerisable compounds and the use thereof in liquid-crystal displays | VCL, ILK, LCP1 | PDE3B 2771/4885PDE3A 2340/4885PTGS2 4474/4885 |
| US-20240072425-A1 | AROMATIC ISOTHIOCYANATES | TRPA1, TRPC1, CRY1 | PDE3B 3262/4885PDE3A 3309/4885PTGS2 4365/4885 |
| US-20080090026-A1 | Liquid-crystal display | KLK3, LPXN, BPHL | PDE3B 980/4885PDE3A 743/4885PTGS2 4553/4885 |
| US-11739265-B2 | Aromatic isothiocyanates | TRPA1, CRY1, FOXM1 | PDE3B 3060/4885PDE3A 3325/4885PTGS2 4025/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.