Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 15/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 12/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 8/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13098816 | 0.90 | HRH3 (0.32) | HRH3 | |
| SCHEMBL13098855 | 0.89 | HRH3 (0.31) | HRH3 | |
| SCHEMBL13098863 | 0.87 | HRH3 (0.34) | HRH3 | |
| SCHEMBL13099028 | 0.86 | PDE10A (0.35) | DGAT1KCNH2ADORA2AHRH3 | |
| SCHEMBL13099108 | 0.85 | DGAT1 (0.40) | DGAT1KCNH2ADORA2AHRH3 | |
| SCHEMBL13099130 | 0.84 | DGAT1 (0.42) | DGAT1KCNH2ADORA2ASOAT1HRH3 | |
| SCHEMBL13098844 | 0.77 | GPR119 (0.37) | DGAT1 | |
| SCHEMBL3107287 | 0.77 | HRH3 (0.43) | HRH3 | |
| SCHEMBL13098840 | 0.76 | GPR119 (0.38) | — | |
| SCHEMBL13098784 | 0.76 | DGAT1 (0.39) | DGAT1KCNH2ADORA2AHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100256048-A1 | POLYPEPTIDE COMPOUND | ASTELLAS PHARMA INC. (JP) | 2010-10-07 | — | — | US | disclosed |
| US-20100256048-A1 | POLYPEPTIDE COMPOUND | ASTELLAS PHARMA INC. (JP) | 2010-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256048-A1 | POLYPEPTIDE COMPOUND | VIP, ANPEP, NPEPPS | DGAT1 3651/4885KCNH2 3669/4885ADORA2A 4727/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.