Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | MAN1B1 | Q9UKM7 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7715057 | 0.95 | KDM4E (0.48) | CXCR4HTR2CMAN1B1HTR2APOLB | |
| Hydrochloric Acid SCHEMBL11228414 | 0.83 | ALDH1A1 (0.47) | HTR2ADPP7ALDH1A1 | |
| SCHEMBL12401336 | 0.80 | KDM4E (0.52) | KDM4EDPP7MEN1KMT2ATDP1 | |
| SCHEMBL4868685 | 0.80 | ALDH1A1 (0.50) | HTR2AKDM4EDPP7NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL11225381 | 0.79 | ALDH1A1 (0.49) | HTR2AKDM4EDPP7NPC1RAB9A | |
| SCHEMBL23023008 | 0.78 | HTR2A (0.55) | HTR2AALDH1A1 | |
| SCHEMBL793526 | 0.78 | PTGS2 (0.59) | KDM4EKMT2APSEN1PSEN2APH1B | |
| SCHEMBL29169544 | 0.78 | PTGS2 (0.59) | KDM4EKMT2APSEN1PSEN2APH1B | |
| SCHEMBL23056654 | 0.78 | PTGS2 (0.59) | KDM4EKMT2APSEN1PSEN2APH1B | |
| Hydrochloric Acid SCHEMBL23004822 | 0.77 | HTR2A (0.54) | HTR2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8846125-B2 | Enaminocarbonyl compounds and their use | INSTYTUT CHEMII ORGANICZNEJ, POLSKA AKADEMIA NAUK (PL) | 2014-09-30 | — | — | US | disclosed |
| CN-102203073-B | Enaminocarbonyl compounds and their use | INST CHEMII ORGANICZNEJ POLSKA | 2014-06-25 | — | — | CN | disclosed |
| EP-2391614-B1 | ENAMINOCARBONYL COMPOUNDS AND THEIR USE | INST CHEMII ORGANICZNEJ POLSKA AKADEMIA NAUK (PL) | 2013-05-29 | — | — | EP | disclosed |
| EP-2391614-A1 | ENAMINOCARBONYL COMPOUNDS AND THEIR USE | Instytut Chemii Organicznej, Polska Akademia Nauk (PL) | 2011-12-07 | — | — | EP | disclosed |
| US-20110274803-A1 | ENAMINOCARBONYL COMPOUNDS AND THEIR USE | INSTYTUT CHEMII ORGANICZNEJ, POLSKA AKADEMIA NAUK (PL) | 2011-11-10 | — | — | US | disclosed |
| CN-102203073-A | Enaminocarbonyl compounds and their use | INST CHEMII ORGANICZNEJ POLSKA | 2011-09-28 | — | — | CN | disclosed |
| WO-2010087727-A1 | ENAMINOCARBONYL COMPOUNDS AND THEIR USE | INSTYTUT CHEMII ORGANICZNEJ, POLSKA AKADEMIA NAUK (PL) | 2010-08-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110274803-A1 | ENAMINOCARBONYL COMPOUNDS AND THEIR USE | TAS2R42, TAS2R41, TAS2R1 | CXCR4 60/4885HTR2C 174/4885MAN1B1 934/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.