SCHEMBL13100511

SCHEMBL13100511

COc1cccc2c(=O)oc(CCCc3nc4c(OC)cccc4c(=O)o3)nc12

nearest known ligand 0.49

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.49
ALDH1A1 P00352 3/20 0.49
HPGD P15428 3/20 0.49
MEN1 O00255 1/20 0.49
CYP1A2 P05177 1/20 0.49
CYP2C9 P11712 1/20 0.49
CYP2C19 P33261 1/20 0.49
KMT2A Q03164 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.47
HSD17B10 Q99714 1/20 0.47
ELANE P08246 4/20 0.44
C1R P00736 1/20 0.44
TNKS O95271 7/20 0.43
TNKS2 Q9H2K2 7/20 0.43
PARP2 Q9UGN5 5/20 0.43
MAOA P21397 1/20 0.42
PARP1 P09874 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12927386 0.91 KDM4E (0.43) KDM4EALDH1A1HPGDMEN1CYP1A2
SCHEMBL1041101 0.91 HSD17B10 (0.50) KDM4EALDH1A1HPGDMEN1CYP1A2
SCHEMBL6339961 0.82 KDM4E (0.46) KDM4EALDH1A1HPGDMEN1CYP1A2
SCHEMBL6351116 0.81 ELANE (0.46) KDM4EALDH1A1HPGDMEN1CYP1A2
SCHEMBL13206697 0.79 ELANE (0.66) KDM4EALDH1A1HPGDMEN1CYP1A2
SCHEMBL29098687 0.78 KDM4E (0.52) KDM4EALDH1A1HPGDMEN1CYP1A2
SCHEMBL7691640 0.77 TNKS (0.47) KDM4EALDH1A1HPGDMEN1CYP1A2
SCHEMBL21790503 0.77 ELANE (0.68) KDM4EALDH1A1HPGDMEN1CYP1A2
SCHEMBL26438946 0.75 KDM4E (0.50) KDM4EALDH1A1HPGDMEN1CYP1A2
SCHEMBL13109026 0.75 KDM4E (0.47) KDM4EALDH1A1HPGDMEN1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8304538-B2 Method of producing benzoxazinone-based compound FUJIFILM CORPORATION (JP) 2012-11-06 US disclosed
US-20100256362-A1 METHOD OF PRODUCING BENZOXAZINONE-BASED COMPOUND FUJIFILM CORPORATION (JP) 2010-10-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100256362-A1 METHOD OF PRODUCING BENZOXAZINONE-BASED COMPOUND SDHA, CYP4X1, SDHB KDM4E 836/4885ALDH1A1 191/4885HPGD 267/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.