Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 5/20 | 0.39 |
| ▸ | CNR2 | P34972 | 5/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27177388 | 0.93 | NPC1 (0.36) | CNR1CNR2MAPK1TDP2L3MBTL1 | |
| SCHEMBL10013961 | 0.93 | NPC1 (0.36) | CNR1CNR2MAPK1TDP2L3MBTL1 | |
| SCHEMBL12379624 | 0.93 | NPC1 (0.36) | CNR1CNR2MAPK1TDP2L3MBTL1 | |
| SCHEMBL11887578 | 0.93 | NPC1 (0.36) | CNR1CNR2MAPK1TDP2L3MBTL1 | |
| SCHEMBL14289888 | 0.88 | PDK2 (0.37) | CNR1CNR2PDK2MAPK1ALDH1A1 | |
| SCHEMBL2000265 | 0.88 | RAB9A (0.35) | CNR1CNR2PDK2MAPK1L3MBTL1 | |
| SCHEMBL22749433 | 0.88 | RAB9A (0.35) | CNR1CNR2PDK2MAPK1L3MBTL1 | |
| SCHEMBL13480894 | 0.88 | RAB9A (0.35) | CNR1CNR2PDK2MAPK1L3MBTL1 | |
| SCHEMBL13109047 | 0.87 | CNR2 (0.39) | CNR1CNR2PDK2CYP19A1ALDH1A1 | |
| SCHEMBL20979466 | 0.87 | NPC1 (0.33) | CNR1CNR2MAPK1TDP2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100252819-A1 | ELECTROACTIVE MATERIALS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100252819-A1 | ELECTROACTIVE MATERIALS | HCN2, HCN4, HCN3 | CNR1 715/4885CNR2 576/4885PDK2 2403/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.