Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.35 |
| ▸ | RELA | Q04206 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 3/20 | 0.34 |
| ▸ | CNR2 | P34972 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 3/20 | 0.33 |
| ▸ | MMP9 | P14780 | 3/20 | 0.33 |
| ▸ | MMP8 | P22894 | 2/20 | 0.33 |
| ▸ | MMP13 | P45452 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13480894 | 1.00 | RAB9A (0.35) | RAB9ANPC1NFKB1NFKB2RELA | |
| SCHEMBL22749433 | 1.00 | RAB9A (0.35) | RAB9ANPC1NFKB1NFKB2RELA | |
| SCHEMBL10357544 | 0.97 | NPC1 (0.34) | RAB9ANPC1NFKB1NFKB2RELA | |
| SCHEMBL11887578 | 0.94 | NPC1 (0.36) | RAB9ANPC1NFKB1NFKB2RELA | |
| SCHEMBL27177388 | 0.94 | NPC1 (0.36) | RAB9ANPC1NFKB1NFKB2RELA | |
| SCHEMBL10013961 | 0.94 | NPC1 (0.36) | RAB9ANPC1NFKB1NFKB2RELA | |
| SCHEMBL12379624 | 0.94 | NPC1 (0.36) | RAB9ANPC1NFKB1NFKB2RELA | |
| SCHEMBL196456 | 0.94 | LMNA (0.36) | RAB9ANPC1NFKB1NFKB2RELA | |
| SCHEMBL197894 | 0.94 | LMNA (0.36) | RAB9ANPC1NFKB1NFKB2RELA | |
| SCHEMBL1795138 | 0.94 | LMNA (0.36) | RAB9ANPC1NFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1973983-B1 | BRANCHED COMPOUNDS AND THEIR USE IN SENSORS | ISIS INNOVATION (GB) | 2016-03-30 | — | — | EP | disclosed |
| US-8319213-B2 | Aryl-aryl dendrimers | ISIS INNOVATION LIMITED (GB) | 2012-11-27 | — | — | US | disclosed |
| US-20110272688-A1 | ARYL-ARYL DENDRIMERS | THE UNIVERSITY COURT OF THE UNIVERSITY OF ST. ANDREWS (GB) | 2011-11-10 | — | — | US | disclosed |
| US-7960725-B2 | Aryl-aryl dendrimers | ISIS INNOVATION LIMITED (GB) | 2011-06-14 | — | — | US | disclosed |
| US-7812323-B2 | Branched compounds and their use in sensors | ISIS INNOVATION LIMITED (GB) | 2010-10-12 | — | — | US | disclosed |
| US-20100127251-A1 | Aryl-Aryl Dendrimers | ISIS INNOVATION LIMITED (GB) | 2010-05-27 | — | — | US | disclosed |
| US-20090314957-A1 | Branched Compounds And Their Use in Sensors | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2009-12-24 | — | — | US | disclosed |
| US-7632576-B2 | Aryl-aryl dendrimers | ISIS INNOVATION LIMITED (GB) | 2009-12-15 | — | — | US | disclosed |
| US-20040169463-A1 | Aryl-aryl dendrimers | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2004-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100127251-A1 | Aryl-Aryl Dendrimers | CLTB, AHR, CD22 | RAB9A 3225/4885NPC1 2810/4885NFKB1 3494/4885 |
| US-20110272688-A1 | ARYL-ARYL DENDRIMERS | CD22, CLTB, AHR | RAB9A 2937/4885NPC1 2904/4885NFKB1 3135/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.