Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | FBP1 | P09467 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7589008 | 0.80 | TDP1 (0.55) | TDP1ALDH1A1HTR2AHTR2CKCNH2 | |
| SCHEMBL12891205 | 0.80 | TDP1 (0.55) | TDP1ALDH1A1HTR2AHTR2CKCNH2 | |
| SCHEMBL7168039 | 0.78 | KMT2A (0.42) | TDP1ALDH1A1TSHR | |
| SCHEMBL27973771 | 0.78 | GAA (0.46) | ALDH1A1 | |
| SCHEMBL28063802 | 0.77 | PSEN1 (0.45) | ALDH1A1 | |
| SCHEMBL13101213 | 0.77 | TDP1 (0.52) | TDP1ALDH1A1HTR2AHTR2CKCNH2 | |
| SCHEMBL12722557 | 0.76 | TDP1 (0.47) | TDP1ALDH1A1EGFRTSHRFBP1 | |
| SCHEMBL13101211 | 0.75 | TDP1 (0.46) | TDP1ALDH1A1HTR2AHTR2CKCNH2 | |
| SCHEMBL13112963 | 0.72 | TDP1 (0.52) | TDP1ALDH1A1HTR2AHTR2CKCNH2 | |
| SCHEMBL27973913 | 0.72 | TAS2R14 (0.47) | TDP1ALDH1A1TSHRFBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100273931-A1 | DECARBOXYLATING BLOCK COPOLYMERS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-10-28 | — | — | US | disclosed |