Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11848869 | 0.82 | HTR6 (0.44) | TDP1ALDH1A1TSHRKMT2AKDM4E | |
| SCHEMBL12373175 | 0.79 | NPY2R (0.50) | TDP1ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL7589008 | 0.78 | TDP1 (0.55) | TDP1ALDH1A1TSHRHTR2AHTR2C | |
| SCHEMBL12891205 | 0.78 | TDP1 (0.55) | TDP1ALDH1A1TSHRHTR2AHTR2C | |
| SCHEMBL13112961 | 0.78 | SRC (0.50) | TDP1ALDH1A1TSHRKMT2ALMNA | |
| SCHEMBL3751933 | 0.77 | ESR1 (0.51) | ALDH1A1KMT2ALMNACA12CA1 | |
| SCHEMBL13101213 | 0.75 | TDP1 (0.52) | TDP1ALDH1A1TSHRHTR2AHTR2C | |
| SCHEMBL23555108 | 0.75 | ALDH1A1 (0.38) | TDP1ALDH1A1KMT2AKDM4EGMNN | |
| SCHEMBL13101210 | 0.75 | TDP1 (0.47) | TDP1ALDH1A1TSHRHTR2AHTR2C | |
| SCHEMBL13112963 | 0.75 | TDP1 (0.52) | TDP1ALDH1A1HTR2AHTR2CKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100273931-A1 | DECARBOXYLATING BLOCK COPOLYMERS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-10-28 | — | — | US | disclosed |