SCHEMBL7589008

SCHEMBL7589008

C=Cc1ccc(S(=O)(=O)C(C)C(C)S(=O)(=O)c2ccc(C=C)cc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.55
ALDH1A1 P00352 4/20 0.46
TSHR P16473 2/20 0.36
HTR2A P28223 2/20 0.36
HTR2C P28335 2/20 0.36
KCNH2 Q12809 2/20 0.36
HDAC8 Q9BY41 2/20 0.35
TAS1R3 Q7RTX0 2/20 0.33
TAS1R1 Q7RTX1 2/20 0.33
CA1 P00915 3/20 0.32
CA2 P00918 3/20 0.32
CA9 Q16790 3/20 0.32
CA7 P43166 2/20 0.32
CA12 O43570 2/20 0.32
CA5A P35218 1/20 0.32
CA5B Q9Y2D0 1/20 0.32
HCRTR1 O43613 1/20 0.32
HCRTR2 O43614 1/20 0.32
MAPT P10636 2/20 0.31
HTT P42858 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12891205 0.88 TDP1 (0.55) TDP1ALDH1A1TSHRHTR2AHTR2C
SCHEMBL13101213 0.84 TDP1 (0.52) TDP1ALDH1A1TSHRHTR2AHTR2C
SCHEMBL13101210 0.80 TDP1 (0.47) TDP1ALDH1A1TSHRHTR2AHTR2C
SCHEMBL13112963 0.80 TDP1 (0.52) TDP1ALDH1A1HTR2AHTR2CKCNH2
SCHEMBL13101211 0.78 TDP1 (0.46) TDP1ALDH1A1TSHRHTR2AHTR2C
SCHEMBL24791574 0.78 TDP1 (0.53) TDP1ALDH1A1TSHRHDAC8TAS1R3
SCHEMBL10225824 0.77 TDP1 (0.49) TDP1ALDH1A1HTR2AHTR2CKCNH2
SCHEMBL13101214 0.76 TDP1 (0.47) TDP1TAS1R3TAS1R1CA1CA2
SCHEMBL4774788 0.76 TDP1 (0.61) TDP1ALDH1A1
SCHEMBL177953 0.75 TDP1 (0.67) TDP1ALDH1A1TSHRHTR2AHTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0869394-B1 Planographic original plate FUJI PHOTO FILM CO LTD (JP) 2002-10-23 EP disclosed
US-6007964-A PHOTOSENSITIVE LAYER CONTAINING POLYMER WITH SIDE CHAIN HAVING SULFONATE GROUPAND AN ACID GENERATING COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1999-12-28 US disclosed
EP-0869394-A1 Planographic original plate FUJI PHOTO FILM CO., LTD. (JP) 1998-10-07 EP disclosed