Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | S100A4 | P26447 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
| ▸ | TYK2 | P29597 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13101474 | 0.86 | AHR (0.39) | ALDH1A1RAB9ATP53TSHRHSD17B10 | |
| SCHEMBL13101419 | 0.74 | CYP1A2 (0.33) | PTPN11RAB9A | |
| SCHEMBL13101423 | 0.74 | AHR (0.45) | IDO1ALDH1A1RAB9AMAPTCYP3A4 | |
| SCHEMBL13101475 | 0.72 | NOTUM (0.40) | IDO1TSHRCNR2 | |
| SCHEMBL13101415 | 0.72 | NOTUM (0.40) | IDO1ALDH1A1RAB9ATP53MAPT | |
| SCHEMBL29364307 | 0.67 | TP53 (0.61) | HTR2BPDE4DIDO1ALDH1A1RXFP1 | |
| SCHEMBL440944 | 0.67 | TP53 (0.61) | HTR2BPDE4DIDO1ALDH1A1RXFP1 | |
| SCHEMBL13101504 | 0.63 | CYP2A6 (0.36) | ALDH1A1MAPT | |
| SCHEMBL7574880 | 0.62 | RAB9A (0.60) | HTR2BPDE4DIDO1ALDH1A1RXFP1 | |
| SCHEMBL2852592 | 0.60 | TP53 (0.57) | HTR2BPDE4DIDO1ALDH1A1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100256109-A1 | Azetidines As EP2 Antagonists | SKERRATT SARAH ELIZABETH | 2010-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256109-A1 | Azetidines As EP2 Antagonists | PTGER2, PTGER1, PTGDR2 | HTR2B 102/4885PDE4D 1013/4885IDO1 276/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.