SCHEMBL13101487

SCHEMBL13101487

CC(C)(C)OC(=O)N1CCNN(C(=O)OC(C)(C)C)CC1

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
MAPK1 P28482 1/20 0.43
HPGD P15428 1/20 0.43
EPHX2 P34913 1/20 0.42
HTT P42858 1/20 0.42
ATM Q13315 1/20 0.42
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
RECQL P46063 1/20 0.41
EPHX1 P07099 1/20 0.41
MAPT P10636 2/20 0.40
KDM4E B2RXH2 1/20 0.40
THRB P10828 1/20 0.40
ALDH1A1 P00352 1/20 0.40
LMNA P02545 1/20 0.40
DDB1 Q16531 1/20 0.40
CRBN Q96SW2 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13101492 0.86 USP2 (0.37) USP2SMN1; SMN2MAPK1HPGDEPHX2
SCHEMBL28306165 0.85 USP2 (0.46) USP2SMN1; SMN2MAPK1HPGDEPHX2
SCHEMBL13101489 0.83 USP2 (0.39) USP2SMN1; SMN2MAPK1HPGDHTT
SCHEMBL132585 0.82 USP2 (0.56) USP2SMN1; SMN2MAPK1HPGDEPHX2
SCHEMBL2220355 0.82 USP2 (0.56) USP2SMN1; SMN2MAPK1HPGDEPHX2
SCHEMBL18294 0.81 USP2 (0.69) USP2SMN1; SMN2HPGDEPHX2HTT
SCHEMBL698803 0.81 USP2 (0.69) USP2SMN1; SMN2HPGDEPHX2HTT
SCHEMBL2125387 0.80 USP2 (0.42) USP2SMN1; SMN2MAPK1HPGDMEN1
SCHEMBL17297711 0.80 USP2 (0.55) USP2SMN1; SMN2MAPK1HPGDEPHX2
SCHEMBL8286 0.80 USP2 (0.58) USP2SMN1; SMN2MAPK1HPGDEPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118414171-A Oligosaccharide complexes and uses 生物技术公司 2024-07-30 CN disclosed
CN-118401538-A Oligosaccharide compounds and complexes 生物技术公司 2024-07-26 CN disclosed
CN-118369122-A Oligosaccharide complex and use thereof 生物技术公司 2024-07-19 CN disclosed
US-8530646-B2 Oxazolidinone derivative having 7-membered hetero ring RESEARCH FOUNDATION ITSUU LABORATORY (JP) 2013-09-10 US disclosed
US-8530646-B2 Oxazolidinone derivative having 7-membered hetero ring RESEARCH FOUNDATION ITSUU LABORATORY (JP) 2013-09-10 US disclosed
US-20100256355-A1 OXAZOLIDINONE DERIVATIVE HAVING 7-MEMBERED HETERO RING Research Foundation ITSUU Laboratory and Shionogi & Co., Ltd. 2010-10-07 US disclosed
US-20100256355-A1 OXAZOLIDINONE DERIVATIVE HAVING 7-MEMBERED HETERO RING Research Foundation ITSUU Laboratory and Shionogi & Co., Ltd. 2010-10-07 US disclosed
EP-2233484-A2 Oxazolidinone derivatives having a 7-membered heterocyclic ring Research Foundation Itsuu Laboratory (JP) 2010-09-29 EP disclosed
EP-2208729-A1 OXAZOLIDINONE DERIVATIVE HAVING 7-MEMBERED HETERO RING Research Foundation Itsuu Laboratory (JP) 2010-07-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100256355-A1 OXAZOLIDINONE DERIVATIVE HAVING 7-MEMBERED HETERO RING NR0B2, NR0B1, NR2C2 USP2 3934/4885SMN1; SMN2 2032/4885MAPK1 3612/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.