SCHEMBL13102769

SCHEMBL13102769

C/C=C/C(=O)Nc1cc(N2CC(CNC(=O)C3CC=C(Cl)S3)OC2=O)ccc1N1CCC(NC(C)=O)C1

nearest known ligand 0.42

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAOA P21397 4/20 0.42
MAOB P27338 3/20 0.42
F10 P00742 15/20 0.41
LMNA P02545 1/20 0.41
PTGS1 P23219 1/20 0.41
CALML3 P27482 1/20 0.41
SDHA P31040 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13103121 0.89 MAOA (0.42) MAOAMAOBF10LMNAPTGS1
SCHEMBL13103196 0.89 F10 (0.42) MAOAMAOBF10LMNAPTGS1
SCHEMBL87717 0.86 F10 (0.58) F10
SCHEMBL14641467 0.86 F10 (0.58) F10
SCHEMBL8210167 0.84 F10 (0.54) MAOAMAOBF10LMNAPTGS1
SCHEMBL8210966 0.82 F10 (0.51) MAOAMAOBF10LMNAPTGS1
SCHEMBL13102687 0.76 F10 (0.50) MAOBF10
SCHEMBL87265 0.75 F10 (0.72) F10
SCHEMBL87238 0.74 F10 (0.59) F10
SCHEMBL13753272 0.74 F10 (0.50) MAOAMAOBF10LMNAPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100267685-A1 Methods For The Prophylaxis And/or Treatment Of Thromboembolic Disorders By Combination Therapy With Substituted Oxazolidinones BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2010-10-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100267685-A1 Methods For The Prophylaxis And/or Treatment Of Thromboembolic Disorders By Combination Therapy With Substituted Oxazolidinones SERPINC1, SDHB, F2 MAOA 162/4885MAOB 40/4885F10 34/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.