Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 5/20 | 0.52 |
| ▸ | CA1 | P00915 | 5/20 | 0.52 |
| ▸ | CA2 | P00918 | 5/20 | 0.52 |
| ▸ | CA9 | Q16790 | 5/20 | 0.52 |
| ▸ | GUSB | P08236 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | GLS | O94925 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | FNTA | P49354 | 3/20 | 0.34 |
| ▸ | FNTB | P49356 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL942527 | 1.00 | CYP3A4 (0.56) | CYP3A4CYP2D6OPRK1LMNATHRB | |
| SCHEMBL941683 | 0.91 | LMNA (0.61) | CYP3A4CYP2D6OPRK1LMNATHRB | |
| SCHEMBL943184 | 0.81 | TYMP (0.43) | CYP3A4CYP2D6OPRK1LMNATHRB | |
| SCHEMBL12427881 | 0.81 | TYMP (0.43) | CYP3A4CYP2D6OPRK1LMNATHRB | |
| SCHEMBL943760 | 0.80 | CA12 (0.51) | CYP3A4CYP2D6OPRK1LMNATHRB | |
| SCHEMBL368130 | 0.78 | LMNA (0.78) | CYP3A4CYP2D6OPRK1LMNATHRB | |
| SCHEMBL13065132 | 0.76 | LMNA (0.74) | CYP3A4CYP2D6OPRK1LMNATHRB | |
| SCHEMBL14043067 | 0.74 | MAPK1 (0.42) | CYP3A4CYP2D6OPRK1LMNATHRB | |
| SCHEMBL15024639 | 0.73 | LMNA (0.80) | CYP3A4CYP2D6OPRK1LMNATHRB | |
| SCHEMBL12264732 | 0.73 | LMNA (0.42) | CYP3A4CYP2D6OPRK1LMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7807394-B2 | Nitro-imidazole hypoxia imaging agents | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2010-10-05 | — | — | US | disclosed |
| US-20090010846-A1 | Nitro-Imidazole Hypoxia Imaging Agents | SIEMENS MEDICAL SOLUTIONS USA, INC. | 2009-01-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090010846-A1 | Nitro-Imidazole Hypoxia Imaging Agents | HIF1AN, HIF1A, HYOU1 | CYP3A4 581/4885CYP2D6 449/4885OPRK1 1267/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.