Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | GLS | O94925 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | FNTA | P49354 | 4/20 | 0.37 |
| ▸ | FNTB | P49356 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | ARG1 | P05089 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL941683 | 0.84 | LMNA (0.61) | MAPK1GLSLMNATHRBCYP2C19 | |
| SCHEMBL14043068 | 0.78 | MMP2 (0.46) | MAPK1CA12CA1CA2CA9 | |
| SCHEMBL12510334 | 0.76 | MAPK1 (0.38) | MAPK1GLSLMNATHRBCYP2C19 | |
| SCHEMBL13104167 | 0.74 | CYP3A4 (0.56) | MAPK1GLSLMNATHRBCYP2C19 | |
| SCHEMBL942527 | 0.74 | CYP3A4 (0.56) | MAPK1GLSLMNATHRBCYP2C19 | |
| SCHEMBL9460145 | 0.67 | — | — | |
| SCHEMBL17369045 | 0.66 | GLS (0.45) | GLSLMNAFNTAFNTBGBA1 | |
| SCHEMBL941529 | 0.65 | LMNA (0.46) | LMNATHRBCYP2C19CYP3A4CYP2D6 | |
| SCHEMBL24380558 | 0.64 | HDAC3 (0.56) | GLSCYP3A4GBA1 | |
| SCHEMBL12825187 | 0.64 | MAOA (0.42) | GBA1CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008124651-A2 | NITRO-IMIDAZOLE HYPOXIA IMAGING AGENTS | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2008-10-16 | — | — | WO | disclosed |