Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.31 |
| ▸ | NMT1 | P30419 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17621278 | 0.70 | MEN1 (0.31) | MAPTNPC1RAB9A | |
| SCHEMBL13106274 | 0.69 | MAPT (0.34) | MAPTNPC1LMNAHTTCHRM4 | |
| SCHEMBL13106159 | 0.69 | PARP1 (0.41) | CHRM4 | |
| SCHEMBL13106193 | 0.69 | MAPK8 (0.36) | MAPTNPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL16006511 | 0.67 | HTT (0.35) | MAPTNPC1RAB9ALMNAHTT | |
| SCHEMBL13106238 | 0.65 | NR4A2 (0.42) | MAPTNPC1RAB9A | |
| SCHEMBL16006487 | 0.65 | LRRK2 (0.33) | CHRM4 | |
| SCHEMBL15146338 | 0.64 | CCR1 (0.45) | MAPTSMN1; SMN2L3MBTL1LMNAHTT | |
| SCHEMBL13647077 | 0.64 | CYP2A6 (0.42) | NPC1RAB9AL3MBTL1 | |
| SCHEMBL9730943 | 0.63 | MAPT (0.47) | MAPTRAB9ASMN1; SMN2L3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7812045-B2 | Antifungal triazole derivatives | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2010-10-12 | — | — | US | disclosed |
| US-20080194661-A1 | Antifungal Triazole Derivatives | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2008-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194661-A1 | Antifungal Triazole Derivatives | ERG28, CYP51A1, CYP3A43 | MAPT 519/4885NPC1 47/4885RAB9A 2353/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.