Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 4/20 | 0.43 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17502187 | 0.83 | KMT2A (0.44) | MAPTL3MBTL1NR4A2CRHR1KDM4E | |
| SCHEMBL437233 | 0.83 | NR4A2 (0.51) | MAPTL3MBTL1NR4A2CRHR1KDM4E | |
| SCHEMBL17502192 | 0.80 | MAPT (0.60) | MAPTL3MBTL1NR4A2CRHR1KDM4E | |
| SCHEMBL9493505 | 0.78 | CYP3A4 (0.36) | NR4A2ALDH1A1 | |
| SCHEMBL17539138 | 0.77 | L3MBTL1 (0.41) | MAPTL3MBTL1NR4A2KDM4EALDH1A1 | |
| SCHEMBL318514 | 0.74 | MAPT (0.64) | MAPTL3MBTL1NR4A2CRHR1KDM4E | |
| SCHEMBL11805706 | 0.74 | MAPT (0.52) | MAPTL3MBTL1KDM4EALDH1A1HPGD | |
| SCHEMBL9730966 | 0.73 | KDM4E (0.38) | MAPTKDM4EALDH1A1HPGDHTT | |
| SCHEMBL7468572 | 0.72 | CYP1A2 (0.42) | MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL12204267 | 0.72 | BDKRB2 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5104884-A | Rheumatic diseases, fungicides | ALKALOIDA VEGYESZETI GYAR (HU) | 1992-04-14 | — | — | US | disclosed |
| EP-0221947-B1 | TRIAZOLYL QUINOLINE DERIVATIVES | ALKALOIDA VEGYéSZETI GYáR (HU) | 1990-11-28 | — | — | EP | disclosed |
| EP-0221947-A1 | TRIAZOLYL QUINOLINE DERIVATIVES. | ALKALOIDA VEGYESZETI GYAR (HU) | 1987-05-20 | — | — | EP | disclosed |
| WO-1986006721-A1 | TRIAZOLYL QUINOLINE DERIVATIVES | ALKALOIDA VEGYÉSZETI GYÁR (HU) | 1986-11-20 | — | — | WO | disclosed |