Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 5/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 5/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 5/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 5/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | SLC22A2 | O15244 | 2/20 | 0.38 |
| ▸ | SLC47A1 | Q96FL8 | 2/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | STAT6 | P42226 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16804791 | 0.87 | — | — | |
| SCHEMBL14641099 | 0.82 | PGR (0.32) | — | |
| SCHEMBL19135850 | 0.82 | — | — | |
| SCHEMBL20749582 | 0.82 | — | — | |
| SCHEMBL16713932 | 0.80 | — | — | |
| SCHEMBL1035502 | 0.80 | HSD11B1 (0.32) | HSD11B1 | |
| SCHEMBL12378023 | 0.78 | HSD11B1 (0.34) | HSD11B1 | |
| SCHEMBL328811 | 0.78 | HSD11B1 (0.32) | HSD11B1 | |
| SCHEMBL12324777 | 0.78 | HSD11B1 (0.36) | HSD11B1 | |
| SCHEMBL8580089 | 0.77 | EPHX2 (0.43) | TSHRALDH1A1NPSR1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 219 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12304894-B2 | Derivatives of adamantyl oxadiazoles and pharmaceutically acceptable solvates, hydrates and salts thereof, pharmaceutical composition comprising same, synthesis method, suitable for use as effective and selective inhibitors of the reductase activity of the enzyme 11-beta dehydrogenase type 1 (11β-HSD1) | PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE (CL) | 2025-05-20 | — | — | US | claimed |
| EP-4407011-A1 | GLASS CRYSTAL-BASED ACTIVELY-CONTROLLABLE BAROCALORIC MATERIAL SOLID STATE PHASE TRANSFORMATION HEAT STORAGE AND HEAT RELEASE METHOD, APPARATUS AND USES | Institute of Metal Research, Chinese Academy of Sciences (CN) | 2024-07-31 | — | — | EP | claimed |
| CN-114350325-B | Glass crystal-based actively controllable solid-state phase change heat storage and release method, device and application of press card material | 中国科学院金属研究所 | 2023-10-03 | — | — | CN | claimed |
| CN-116793129-A | Fine controllable heat release device based on plastic crystal glass crystal phase, heat release method and application thereof | 中国科学院金属研究所 | 2023-09-22 | — | — | CN | claimed |
| WO-2023133909-A1 | GLASS CRYSTAL-BASED ACTIVELY-CONTROLLABLE BAROCALORIC MATERIAL SOLID STATE PHASE TRANSFORMATION HEAT STORAGE AND HEAT RELEASE METHOD, APPARATUS AND USES | 中国科学院金属研究所 | 2023-07-20 | — | — | WO | claimed |
| CN-115468688-A | Method for realizing pressure sensing based on response of glass crystal to pressure and application thereof | 中国科学院金属研究所 | 2022-12-13 | — | — | CN | claimed |
| US-20220194909-A1 | DERIVATIVES OF ADAMANTYL OXADIAZOLES AND PHARMACEUTICALLY ACCEPTABLE SOLVATES, HYDRATES AND SALTS THEREOF, PHARMACEUTICAL COMPOSITION COMPRISING SAME, SYNTHESIS METHOD, SUITABLE FOR USE AS EFFECTIVE AND SELECTIVE INHIBITORS OF THE REDUCTASE ACTIVITY OF THE ENZYME 11-BETA DEHYDROGENASE TYPE 1 (11B-HSD1) | PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE (CL) | 2022-06-23 | — | — | US | claimed |
| CN-114350325-A | Glass crystal-based active and controllable solid-state phase change heat storage and heat release method and device for card pressing material and application | 中国科学院金属研究所 | 2022-04-15 | — | — | CN | claimed |
| WO-2020210922-A1 | DERIVATIVES OF ADAMANTYL OXADIAZOLES AND PHARMACEUTICALLY ACCEPTABLE SOLVATES, HYDRATES AND SALTS THEREOF, PHARMACEUTICAL COMPOSITION COMPRISING SAME, SYNTHESIS METHOD, SUITABLE FOR USE AS EFFECTIVE AND SELECTIVE INHIBITORS OF THE REDUCTASE ACTIVITY OF THE ENZYME 11-BETA DEHYDROGENASE TYPE 1 (11Β-HSD1) | PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE (CL) | 2020-10-22 | — | — | WO | claimed |
| EP-3636641-A1 | ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES | CYNORA GMBH (DE) | 2020-04-15 | — | — | EP | claimed |
| EP-2272825-B1 | Protected amino hydroxy adamantane carboxylic acid and process for its preparation | ASTRAZENECA AB (SE) | 2015-11-04 | — | — | EP | claimed |
| EP-1948736-B1 | PROCESS FOR PREPARING FLAKE-FORM PARTICLES | BASF SE (DE) | 2011-03-16 | — | — | EP | claimed |
| EP-2272825-A2 | N-Protected amino hydroxy adamantane carboxylic acid and process for its preparation | Bristol-Myers Squibb Company (US) | 2011-01-12 | — | — | EP | claimed |
| US-20100062244-A1 | Process for Preparing Flake-Form Particles | CIBA CORPORATION (US) | 2010-03-11 | — | — | US | claimed |
| EP-1948736-A1 | PROCESS FOR PREPARING FLAKE-FORM PARTICLES | Ciba Holding Inc. (CH) | 2008-07-30 | — | — | EP | claimed |
| CN-101031595-A | One-component cationic palladium pre-initiator for the latent polymerization of cycloolefins | PROMERUS LLC (US) | 2007-09-05 | — | — | CN | claimed |
| WO-2007057328-A1 | PROCESS FOR PREPARING FLAKE-FORM PARTICLES | CIBA HOLDING INC. (CH) | 2007-05-24 | — | — | WO | claimed |
| EP-1559710-A2 | Cyclopropyl-fused pyrrolidine-based inhibitors of dipeptidyl peptidase IV, process for their preparation and their use | Bristol-Myers Squibb Company (US) | 2005-08-03 | — | — | EP | claimed |
| US-4894180-A | Liquid crystal optical element | FUJI PHOTO FILM CO., LTD. (JP) | 1990-01-16 | — | — | US | claimed |
| EP-0178668-A2 | Process for preparing rimantadine | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-04-23 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220194909-A1 | DERIVATIVES OF ADAMANTYL OXADIAZOLES AND PHARMACEUTICALLY ACCEPTABLE SOLVATES, HYDRATES AND SALTS THEREOF, PHARMACEUTICAL COMPOSITION COMPRISING SAME, SYNTHESIS METHOD, SUITABLE FOR USE AS EFFECTIVE AND SELECTIVE INHIBITORS OF THE REDUCTASE ACTIVITY OF THE ENZYME 11-BETA DEHYDROGENASE TYPE 1 (11B-HSD1) | HSD11B1, HSD11B2, CYP11B1 | GRIN2D 483/4885GRIN3B 726/4885GRIN1 438/4885 |
| US-12304894-B2 | Derivatives of adamantyl oxadiazoles and pharmaceutically acceptable solvates, hydrates and salts thereof, pharmaceutical composition comprising same, synthesis method, suitable for use as effective and selective inhibitors of the reductase activity of the enzyme 11-beta dehydrogenase type 1 (11β-HSD1) | HSD11B1, HSD11B2, HSD17B1 | GRIN2D 495/4885GRIN3B 803/4885GRIN1 361/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.