Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13108706 | 0.93 | DGAT1 (0.62) | DGAT1CA12CA1CA2CA7 | |
| SCHEMBL11174091 | 0.92 | DGAT1 (0.50) | DGAT1CYP1A2MEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL17512889 | 0.91 | DGAT1 (0.60) | DGAT1CA12CA1CA2CA7 | |
| Hydrochloric Acid SCHEMBL20766398 | 0.91 | DGAT1 (0.60) | DGAT1CA12CA1CA2CA7 | |
| Hydrochloric Acid SCHEMBL3736474 | 0.90 | DGAT1 (0.49) | DGAT1CYP1A2MEN1KMT2AMAPT | |
| SCHEMBL10040530 | 0.86 | DGAT1 (0.56) | DGAT1CA12CA1CA2CA7 | |
| Hydrochloric Acid SCHEMBL2327193 | 0.84 | DGAT1 (0.55) | DGAT1CA12CA1CA2CA7 | |
| SCHEMBL15294298 | 0.84 | DGAT1 (0.55) | DGAT1CA12CA1CA2CA7 | |
| SCHEMBL3440192 | 0.84 | ESR1 (0.59) | DGAT1CA12CA1CA2CA7 | |
| SCHEMBL15650610 | 0.83 | CYP3A4 (0.60) | DGAT1ESR1ESR2CYP1A2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7816520-B2 | Such as 1,4-Bis[5,6-(4,4'-dihydroxy)-diphenyl-1,2,4-triazin-3-yl]benzene; cosmetics for human skin, hair | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2010-10-19 | — | — | US | disclosed |
| US-7816520-B2 | Such as 1,4-Bis[5,6-(4,4'-dihydroxy)-diphenyl-1,2,4-triazin-3-yl]benzene; cosmetics for human skin, hair | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2010-10-19 | — | — | US | disclosed |
| US-20080267892-A1 | Such as 1,4-Bis[5,6-(4,4'-dihydroxy)-diphenyl-1,2,4-triazin-3-yl]benzene; cosmetics for human skin, hair | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2008-10-30 | — | — | US | disclosed |
| US-20080267892-A1 | Such as 1,4-Bis[5,6-(4,4'-dihydroxy)-diphenyl-1,2,4-triazin-3-yl]benzene; cosmetics for human skin, hair | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2008-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080267892-A1 | Such as 1,4-Bis[5,6-(4,4'-dihydroxy)-diphenyl-1,2,4-triazin-3-yl]benzene; cosmetics for human skin, hair | TYR, H1-0, TELO2 | DGAT1 2110/4885CA12 2916/4885CA1 3092/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.