Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | WDR5 | P61964 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2327193 | 0.98 | DGAT1 (0.55) | DGAT1GAAKMT2AALDH1A1LMNA | |
| SCHEMBL13108706 | 0.93 | DGAT1 (0.62) | DGAT1KMT2AALDH1A1LMNACA12 | |
| Hydrochloric Acid SCHEMBL20766398 | 0.91 | DGAT1 (0.60) | DGAT1KMT2AALDH1A1LMNACA12 | |
| Hydrochloric Acid SCHEMBL17512889 | 0.91 | DGAT1 (0.60) | DGAT1KMT2AALDH1A1LMNACA12 | |
| SCHEMBL13108731 | 0.86 | DGAT1 (0.56) | DGAT1KMT2AALDH1A1LMNACA12 | |
| SCHEMBL3440192 | 0.84 | ESR1 (0.59) | DGAT1KMT2AALDH1A1LMNACA12 | |
| SCHEMBL15294298 | 0.84 | DGAT1 (0.55) | DGAT1GAAKMT2AALDH1A1LMNA | |
| SCHEMBL5498688 | 0.83 | DGAT1 (0.53) | DGAT1GAAKMT2AALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL3440191 | 0.83 | ESR1 (0.57) | DGAT1KMT2AALDH1A1LMNACA12 | |
| SCHEMBL15650610 | 0.83 | CYP3A4 (0.60) | DGAT1ALDH1A1LMNAESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119059933-A | Method for synthesizing aryl nitrile and spiro isoindole compounds by using trivalent rhodium as catalyst | 沈阳师范大学 | 2024-12-03 | — | — | CN | disclosed |
| CN-114560790-B | Biphenyl-2-nitrile compound and preparation method thereof | 赣南师范大学 | 2024-02-20 | — | — | CN | disclosed |
| CN-115710227-A | Preparation method of indenoisoquinoline derivative | 广东工业大学 | 2023-02-24 | — | — | CN | disclosed |
| CN-114560790-A | Biphenyl-2-nitrile compound and preparation method thereof | 赣南师范大学 | 2022-05-31 | — | — | CN | disclosed |
| CN-109438264-B | Polysubstituted indenamine derivative and preparation method thereof | 华侨大学 | 2021-06-01 | — | — | CN | disclosed |
| WO-2020219287-A1 | CAMPTOTHECIN DERIVATIVES | IMMUNOGEN, INC. (US) | 2020-10-29 | — | — | WO | disclosed |
| EP-3622968-A1 | COMPOSITIONS AND METHODS FOR DELIVERING A SUBSTANCE TO A BIOLOGICAL TARGET | The General Hospital Corporation (US) | 2020-03-18 | — | — | EP | disclosed |
| US-8207199-B2 | Azole compound | ASTELLAS PHARMA INC. (JP) | 2012-06-26 | — | — | US | disclosed |
| US-20110118311-A1 | AZOLE COMPOUND | ASTELLAS PHARMA INC. (JP) | 2011-05-19 | — | — | US | disclosed |
| US-7799947-B2 | In vivo imaging compounds | HAMMERSMITH IMANET LIMITED (GB) | 2010-09-21 | — | — | US | disclosed |
| US-20090155168-A1 | IN VIVO IMAGING COMPOUNDS | GE HEALTHCARE LIMITED (GB) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110118311-A1 | AZOLE COMPOUND | FAAH, FAAH2, TRPV1 | DGAT1 758/4885GAA 3393/4885KMT2A 1802/4885 |
| US-20090155168-A1 | IN VIVO IMAGING COMPOUNDS | GRIN1, GRIN2B, GRIN3B | DGAT1 2577/4885GAA 4417/4885KMT2A 1278/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.