Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | WDR5 | P61964 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | RARA | P10276 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 1/20 | 0.41 |
| ▸ | RARG | P13631 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3736474 | 0.98 | DGAT1 (0.49) | DGAT1MAPTSMN1; SMN2L3MBTL1WDR5 | |
| SCHEMBL13108731 | 0.92 | DGAT1 (0.56) | DGAT1MAPTSMN1; SMN2L3MBTL1WDR5 | |
| SCHEMBL437904 | 0.88 | DGAT1 (0.52) | DGAT1MAPTSMN1; SMN2ALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL336974 | 0.86 | DGAT1 (0.50) | DGAT1MAPTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL13108706 | 0.85 | DGAT1 (0.62) | DGAT1SMN1; SMN2HPGDALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL6960112 | 0.84 | DGAT1 (0.49) | DGAT1MAPTSMN1; SMN2ALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL17512889 | 0.83 | DGAT1 (0.60) | DGAT1SMN1; SMN2HPGDALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL20766398 | 0.83 | DGAT1 (0.60) | DGAT1SMN1; SMN2HPGDALDH1A1MEN1 | |
| SCHEMBL3739816 | 0.81 | LTA4H (0.53) | DGAT1MAPTSMN1; SMN2HPGDALDH1A1 | |
| Hydrochloric Acid SCHEMBL3739815 | 0.80 | LTA4H (0.52) | DGAT1MAPTSMN1; SMN2HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115710227-A | Preparation method of indenoisoquinoline derivative | 广东工业大学 | 2023-02-24 | — | — | CN | disclosed |
| US-4379155-A | 3,5-Disubstituted-1H-1,2,4-triazole derivatives | GRUPPO LEPETIT S.P.A. (IT) | 1983-04-05 | — | — | US | disclosed |
| US-4370336-A | OXYTOCICS | GRUPPO LEPETIT S.P.A. (IT) | 1983-01-25 | — | — | US | disclosed |
| US-4313950-A | Antireproductive tricyclic ortho-fused nitrogen containing compounds | GRUPPO LEPETIT S.P.A. (IT) | 1982-02-02 | — | — | US | disclosed |
| US-4275066-A | 1,2,4-TRIAZOLO(5.1A)ISOINDOZE, TRIAZOLO(5.1A) ISOQUINOLINE OR 1,2,4,-TRIAZOLO (5.1A)(2) BENZAZEPINE CONTRACEPTIVES | GRUPPO LEPETIT S.P.A. (IT) | 1981-06-23 | — | — | US | disclosed |