Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13110288 | 0.74 | MAPT (0.37) | OGAALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL19083302 | 0.71 | GBA1 (0.55) | OGA | |
| SCHEMBL12693220 | 0.70 | ALDH1A1 (0.46) | ALDH1A1 | |
| SCHEMBL25160376 | 0.70 | ALDH1A1 (0.50) | ALDH1A1 | |
| SCHEMBL27293085 | 0.67 | ALDH1A1 (0.46) | ALDH1A1 | |
| SCHEMBL6923375 | 0.65 | OGA (0.39) | OGAALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL6924333 | 0.65 | OGA (0.39) | OGAALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL6923371 | 0.65 | OGA (0.39) | OGAALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL6924328 | 0.65 | OGA (0.39) | OGAALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL24535963 | 0.65 | GBA1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7820699-B2 | Cyclic amines | HOFFMANN-LA ROCHE INC. (US) | 2010-10-26 | — | — | US | disclosed |